Selective proton-observed, carbon-edited (selPOCE) MRS method for measurement of glutamate and glutamine <sup>13</sup> C-labeling in the human frontal cortex.

De Feyter, Henk M; Herzog, Raimund I; Steensma, Bart R; Klomp, Dennis W J; Brown, Peter B; Mason, Graeme F; Rothman, Douglas L; de Graaf, Robin A

Selective proton-observed, carbon-edited (selPOCE) MRS method for measurement of glutamate and glutamine ¹³ C-labeling in the human frontal cortex.

De Feyter, Henk M; Herzog, Raimund I; Steensma, Bart R; Klomp, Dennis W J; Brown, Peter B; Mason, Graeme F; Rothman, Douglas L; de Graaf, Robin A.

Afiliação

De Feyter HM; Department of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, Connecticut, USA.
Herzog RI; Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Steensma BR; Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands.
Klomp DWJ; Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands.
Brown PB; Department of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, Connecticut, USA.
Mason GF; Department of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, Connecticut, USA.
Rothman DL; Department of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, Connecticut, USA.
de Graaf RA; Department of Biomedical Engineering, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, Connecticut, USA.

Magn Reson Med ; 80(1): 11-20, 2018 07.

Article em En | MEDLINE | ID: mdl-29134686

Assuntos

Carbono/química; Lobo Frontal/diagnóstico por imagem; Ácido Glutâmico/química; Glutamina/química; Espectroscopia de Ressonância Magnética/métodos; Adulto; Mapeamento Encefálico; Feminino; Voluntários Saudáveis; Humanos; Imageamento Tridimensional; Cinética; Masculino; Neuroimagem/métodos; Neurotransmissores/metabolismo; Segurança do Paciente; Imagens de Fantasmas; Prótons; Ondas de Rádio; Adulto Jovem

Palavras-chave

13C; MRS; frontal lobe; human

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carbono / Espectroscopia de Ressonância Magnética / Ácido Glutâmico / Lobo Frontal / Glutamina Tipo de estudo: Guideline Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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