Your browser doesn't support javascript.
loading
Factors to improve the interobserver agreement for gastric atrophy and intestinal metaplasia: consensus of definition and criteria.
Kim, Sung Sun; Kook, Myeong-Cherl; Shin, Ok-Ran; Kim, Hee Sung; Bae, Han-Ik; Seo, An Na; Park, Do Youn; Choi, Il Ju; Kim, Young-Il; Nam, Byung Ho; Kim, Sohee.
Afiliação
  • Kim SS; Department of Pathology, Chonnam National University Hospital, Gwangju, South Korea.
  • Kook MC; Center for Gastric Cancer, National Cancer Center, Goyang, South Korea.
  • Shin OR; Department of Pathology, Uijeongbu St Mary's Hospital, Catholic University of Korea, Gyeonggi-do, South Korea.
  • Kim HS; Deparment of Pathology, School of Medicine, Chung-Ang University, Seoul, South Korea.
  • Bae HI; Department of Pathology, School of Medicine, Kyungpook National University, Chilgok Hospital, Daegu, South Korea.
  • Seo AN; Department of Pathology, School of Medicine, Kyungpook National University, Chilgok Hospital, Daegu, South Korea.
  • Park DY; Department of Pathology, School of Medicine, Pusan National University, Busan, South Korea.
  • Choi IJ; Center for Gastric Cancer, National Cancer Center, Goyang, South Korea.
  • Kim YI; Center for Gastric Cancer, National Cancer Center, Goyang, South Korea.
  • Nam BH; Biometric Research Branch, Research Institute, National Cancer Center, Goyang, South Korea.
  • Kim S; Biometric Research Branch, Research Institute, National Cancer Center, Goyang, South Korea.
Histopathology ; 72(5): 838-845, 2018 Apr.
Article em En | MEDLINE | ID: mdl-29161756
AIMS: Intestinal metaplasia and atrophy of the gastric mucosa are associated with Helicobacter pylori infection and are considered premalignant lesions. The updated Sydney system is used for these parameters, but experienced pathologists and consensus processes are required for interobserver agreement. We sought to determine the influence of the consensus process on the assessment of intestinal metaplasia and atrophy. METHODS AND RESULTS: Two study sets were used: consensus and validation. The consensus set was circulated and five gastrointestinal pathologists evaluated them independently using the updated Sydney system. The consensus of the definitions was then determined at the first consensus meeting. The same set was recirculated to determine the effect of the consensus. The second consensus meeting was held to standardise the grading criteria and the validation set was circulated to determine the influence. Two additional circulations were performed to assess the maintainance of consensus and intraobserver variability. Interobserver agreement of intestinal metaplasia and atrophy was improved through the consensus process (intestinal metaplasia: baseline κ = 0.52 versus final κ = 0.68, P = 0.006; atrophy: baseline κ = 0.19 versus final κ = 0.43, P < 0.001). Higher interobserver agreement in atrophy was observed after consensus regarding the definition (pre-consensus: κ = 0.19 versus post-consensus: κ = 0.34, P = 0.001). There was improved interobserver agreement in intestinal metaplasia after standardisation of the grading criteria (pre-standardisation: κ = 0.56 versus post-standardisation: κ = 0.71, P = 0.010). CONCLUSIONS: This study suggests that interobserver variability regarding intestinal metaplasia and atrophy may result from lack of a precise definition and fine criteria, and can be reduced by consensus of definition and standardisation of grading criteria.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lesões Pré-Cancerosas / Gastropatias / Consenso / Gradação de Tumores / Enteropatias Tipo de estudo: Diagnostic_studies / Guideline Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lesões Pré-Cancerosas / Gastropatias / Consenso / Gradação de Tumores / Enteropatias Tipo de estudo: Diagnostic_studies / Guideline Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article