Vitamin D status is associated with underweight and stunting in children aged 6-36 months residing in the Ecuadorian Andes.
Public Health Nutr
; 21(11): 1974-1985, 2018 08.
Article
em En
| MEDLINE
| ID: mdl-29162164
ABSTRACT
OBJECTIVE:
There is limited knowledge on vitamin D status of children residing in the Andes and its association with undernutrition. We evaluated the vitamin D status of children residing in a low socio-economic status (SES) setting in the Ecuadorian Andes and assessed the association between vitamin D status, stunting and underweight. We hypothesized that children who were underweight would have lower serum 25-hydroxyvitamin D (25(OH)D) levels and lower 25(OH)D levels would be associated with a higher risk of stunting.DESIGN:
We conducted a cross-sectional secondary analysis of a randomized controlled trial, the Vitamin A, Zinc and Pneumonia study. Children had serum 25(OH)D concentrations measured. A sensitivity analysis was undertaken to determine a vitamin D cut-off specific for our endpoints. Associations between serum 25(OH)D and underweight (defined as weight-for-age Z-score≤-1) and stunting (defined as height-for-age Z-score≤-2) were assessed using multivariate logistic regression.SETTING:
Children residing in five low-SES peri-urban neighbourhoods near Quito, Ecuador.SUBJECTS:
Children (n 516) aged 6-36 months.RESULTS:
Mean serum 25(OH)D concentration was 58·0 (sd 17·7) nmol/l. Sensitivity analysis revealed an undernutrition-specific 25(OH)D cut-off of <42·5 nmol/l; 18·6 % of children had serum 25(OH)D<42·5 nmol/l. Children who were underweight were more likely to have serum 25(OH)D<42·5 nmol/l (adjusted OR (aOR)=2·0; 95 % CI 1·2, 3·3). Children with low serum 25(OH)D levels were more likely to be stunted (aOR=2·8; 95 % CI 1·6, 4·7).CONCLUSIONS:
Low serum 25(OH)D levels were more common in underweight and stunted Ecuadorian children.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Magreza
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Vitamina D
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Deficiência de Vitamina D
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Transtornos do Crescimento
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Child, preschool
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Female
/
Humans
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Infant
/
Male
País/Região como assunto:
America do sul
/
Ecuador
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article