Melatonin-Induced Changes in Cytosolic Calcium Might be Responsible for Apoptosis Induction in Tumour Cells.

Chovancova, Barbora; Hudecova, Sona; Lencesova, Lubomira; Babula, Petr; Rezuchova, Ingeborg; Penesova, Adela; Grman, Marian; Moravcik, Roman; Zeman, Michal; Krizanova, Olga

Chovancova, Barbora; Hudecova, Sona; Lencesova, Lubomira; Babula, Petr; Rezuchova, Ingeborg; Penesova, Adela; Grman, Marian; Moravcik, Roman; Zeman, Michal; Krizanova, Olga.

Afiliação

Chovancova B; Institute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.
Hudecova S; Institute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.
Lencesova L; Institute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.
Babula P; Department of Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
Rezuchova I; Institute of Virology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.
Penesova A; Institute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.
Grman M; Institute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.
Moravcik R; Department of Animal Physiology and Ethology, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.
Zeman M; Institute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.
Krizanova O; Institute of Clinical and Translational Research, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.

Cell Physiol Biochem ; 44(2): 763-777, 2017.

Article em En | MEDLINE | ID: mdl-29169174

Assuntos

Apoptose/efeitos dos fármacos; Cálcio/metabolismo; Melatonina/toxicidade; Linhagem Celular Tumoral; Citosol/metabolismo; Estresse do Retículo Endoplasmático/efeitos dos fármacos; Humanos; Receptores de Inositol 1,4,5-Trifosfato/antagonistas & inibidores; Receptores de Inositol 1,4,5-Trifosfato/genética; Microscopia de Fluorescência; Interferência de RNA; RNA Interferente Pequeno/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Trocador de Sódio e Cálcio/antagonistas & inibidores; Trocador de Sódio e Cálcio/genética; Trocador de Sódio e Cálcio/metabolismo; Fator de Transcrição CHOP/genética; Fator de Transcrição CHOP/metabolismo; Proteína 1 de Ligação a X-Box/genética; Proteína 1 de Ligação a X-Box/metabolismo

Palavras-chave

Apoptosis; Calcium; Cancer; ER-stress; Melatonin; Reactive oxygen species

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cálcio / Apoptose / Melatonina Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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