Optogenetic Retinal Gene Therapy with the Light Gated GPCR Vertebrate Rhodopsin.

Gaub, Benjamin M; Berry, Michael H; Visel, Meike; Holt, Amy; Isacoff, Ehud Y; Flannery, John G

Gaub, Benjamin M; Berry, Michael H; Visel, Meike; Holt, Amy; Isacoff, Ehud Y; Flannery, John G.

Afiliação

Gaub BM; Department of Biosystems Science and Engineering (D-BSSE), Eidgenössische Technische Hochschule (ETH) Zürich, Basel, Switzerland.
Berry MH; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.
Visel M; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.
Holt A; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.
Isacoff EY; Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, CA, USA.
Flannery JG; Physical Bioscience Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.

Methods Mol Biol ; 1715: 177-189, 2018.

Article em En | MEDLINE | ID: mdl-29188513

Assuntos

Terapia Genética/métodos; Neurônios/metabolismo; Optogenética/métodos; Retina/metabolismo; Doenças Retinianas/terapia; Rodopsina/genética; Animais; Comportamento Animal; Luz; Camundongos; Camundongos Endogâmicos C57BL; Doenças Retinianas/genética

Palavras-chave

Congenital blindness; Light-gated receptors; Optogenetics; Retinal gene therapy; Retinitis pigmentosa; Translational medicine; Visual prosthetics

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Retina / Doenças Retinianas / Rodopsina / Terapia Genética / Optogenética / Neurônios Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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