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A type 2 diabetes-associated SNP in KCNQ1 (rs163184) modulates the binding activity of the locus for Sp3 and Lsd1/Kdm1a, potentially affecting CDKN1C expression.
Hiramoto, Masaki; Udagawa, Haruhide; Ishibashi, Naoko; Takahashi, Eri; Kaburagi, Yasushi; Miyazawa, Keisuke; Funahashi, Nobuaki; Nammo, Takao; Yasuda, Kazuki.
Afiliação
  • Hiramoto M; Department of Metabolic Disorder, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.
  • Udagawa H; Department of Metabolic Disorder, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.
  • Ishibashi N; Department of Metabolic Disorder, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.
  • Takahashi E; Department of Diabetic Complications, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.
  • Kaburagi Y; Department of Diabetic Complications, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.
  • Miyazawa K; Department of Biochemistry, Tokyo Medical University, Tokyo 160-8402, Japan.
  • Funahashi N; Department of Metabolic Disorder, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.
  • Nammo T; Department of Metabolic Disorder, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.
  • Yasuda K; Department of Metabolic Disorder, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.
Int J Mol Med ; 41(2): 717-728, 2018 Feb.
Article em En | MEDLINE | ID: mdl-29207083
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Canal de Potássio KCNQ1 / Inibidor de Quinase Dependente de Ciclina p57 / Fator de Transcrição Sp3 / Histona Desmetilases Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Canal de Potássio KCNQ1 / Inibidor de Quinase Dependente de Ciclina p57 / Fator de Transcrição Sp3 / Histona Desmetilases Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article