Ezrin mediates both HGF/Met autocrine and non-autocrine signaling-induced metastasis in melanoma.

Huang, Liping; Qin, Yifei; Zuo, Qiang; Bhatnagar, Kavita; Xiong, Jingbo; Merlino, Glenn; Yu, Yanlin

Huang, Liping; Qin, Yifei; Zuo, Qiang; Bhatnagar, Kavita; Xiong, Jingbo; Merlino, Glenn; Yu, Yanlin.

Afiliação

Huang L; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institutes, National Institutes of Health, Bethesda, MD, 20892-4264.
Qin Y; Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Zuo Q; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institutes, National Institutes of Health, Bethesda, MD, 20892-4264.
Bhatnagar K; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institutes, National Institutes of Health, Bethesda, MD, 20892-4264.
Xiong J; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institutes, National Institutes of Health, Bethesda, MD, 20892-4264.
Merlino G; Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, People's Republic of China.
Yu Y; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institutes, National Institutes of Health, Bethesda, MD, 20892-4264.

Int J Cancer ; 142(8): 1652-1663, 2018 04 15.

Article em En | MEDLINE | ID: mdl-29210059

Assuntos

Comunicação Autócrina/genética; Proteínas do Citoesqueleto/genética; Fator de Crescimento de Hepatócito/genética; Melanoma/genética; Melanoma/patologia; Metástase Neoplásica/genética; Proteínas Proto-Oncogênicas c-met/genética; Animais; Linhagem Celular Tumoral; Movimento Celular/genética; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Metástase Neoplásica/patologia; Regiões Promotoras Genéticas/genética; Transdução de Sinais/genética

Palavras-chave

Ezrin; HGF; melanoma; metastasis; therapeutic target

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento de Hepatócito / Comunicação Autócrina / Proteínas Proto-Oncogênicas c-met / Proteínas do Citoesqueleto / Melanoma / Metástase Neoplásica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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