Starring or Supporting Role? Satellite Cells and Skeletal Muscle Fiber Size Regulation.
Physiology (Bethesda)
; 33(1): 26-38, 2018 Jan 01.
Article
em En
| MEDLINE
| ID: mdl-29212890
ABSTRACT
Recent loss-of-function studies show that satellite cell depletion does not promote sarcopenia or unloading-induced atrophy, and does not prevent regrowth. Although overload-induced muscle fiber hypertrophy is normally associated with satellite cell-mediated myonuclear accretion, hypertrophic adaptation proceeds in the absence of satellite cells in fully grown adult mice, but not in young growing mice. Emerging evidence also indicates that satellite cells play an important role in remodeling the extracellular matrix during hypertrophy.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Músculo Esquelético
/
Fibras Musculares Esqueléticas
/
Células Satélites de Músculo Esquelético
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article