T Cells Expressing Checkpoint Receptor TIGIT Are Enriched in Follicular Lymphoma Tumors and Characterized by Reversible Suppression of T-cell Receptor Signaling.

Josefsson, Sarah E; Huse, Kanutte; Kolstad, Arne; Beiske, Klaus; Pende, Daniela; Steen, Chloé B; Inderberg, Else Marit; Lingjærde, Ole Christian; Østenstad, Bjørn; Smeland, Erlend B; Levy, Ronald; Irish, Jonathan M; Myklebust, June H

Josefsson, Sarah E; Huse, Kanutte; Kolstad, Arne; Beiske, Klaus; Pende, Daniela; Steen, Chloé B; Inderberg, Else Marit; Lingjærde, Ole Christian; Østenstad, Bjørn; Smeland, Erlend B; Levy, Ronald; Irish, Jonathan M; Myklebust, June H.

Afiliação

Josefsson SE; Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway.
Huse K; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
Kolstad A; Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway.
Beiske K; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
Pende D; Department of Oncology, Division of Cancer Medicine, Oslo University Hospital, Oslo, Norway.
Steen CB; Department of Pathology, Oslo University Hospital, Oslo, Norway.
Inderberg EM; Immunology Laboratory, Ospedale Policlinico San Martino, Genova, Italy.
Lingjærde OC; Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway.
Østenstad B; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.
Smeland EB; Department of Computer Science, University of Oslo, Oslo, Norway.
Levy R; Department of Cellular Therapy, Oslo University Hospital, Oslo, Norway.
Irish JM; Centre for Cancer Biomedicine, University of Oslo, Oslo, Norway.
Myklebust JH; Department of Computer Science, University of Oslo, Oslo, Norway.

Clin Cancer Res ; 24(4): 870-881, 2018 02 15.

Article em En | MEDLINE | ID: mdl-29217528

Assuntos

Linfoma Folicular/genética; Receptores de Antígenos de Linfócitos T/genética; Receptores Imunológicos/genética; Transdução de Sinais/genética; Antígenos de Diferenciação de Linfócitos T/genética; Antígenos de Diferenciação de Linfócitos T/metabolismo; Linfócitos T CD8-Positivos/metabolismo; Citocinas/metabolismo; Perfilação da Expressão Gênica/métodos; Regulação Neoplásica da Expressão Gênica; Humanos; Linfoma Folicular/metabolismo; Receptores de Antígenos de Linfócitos T/metabolismo; Receptores Imunológicos/metabolismo; Subpopulações de Linfócitos T/metabolismo; Microambiente Tumoral/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T / Receptores Imunológicos / Transdução de Sinais / Linfoma Folicular Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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