Acute basophilic leukemia associated with the t(16;21)(p11;q22)/FUS-ERG fusion gene.
Clin Case Rep
; 5(12): 1938-1944, 2017 12.
Article
em En
| MEDLINE
| ID: mdl-29225830
ABSTRACT
We herein report a rare case of acute basophilic leukemia with t(16;21)(p11;q22) generating the FUS-ERG fusion gene. The basophilic nature of leukemia blasts was demonstrated by cytomorphology, toluidine blue metachromasia, mature basophil-associated antigen expression, and characteristic granules under electron microscopy. The molecular link between t(16;21)/FUS-ERG and basophilic differentiation remains unclear.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Risk_factors_studies
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article