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Intracerebroventricular delivery of hematopoietic progenitors results in rapid and robust engraftment of microglia-like cells.
Capotondo, Alessia; Milazzo, Rita; Garcia-Manteiga, Jose M; Cavalca, Eleonora; Montepeloso, Annita; Garrison, Brian S; Peviani, Marco; Rossi, Derrick J; Biffi, Alessandra.
Afiliação
  • Capotondo A; San Raffaele Telethon Institute for Gene Therapy, Division of Regenerative Medicine, Stem Cell and Gene Therapy, San Raffaele Scientific Institute, Milano, Italy.
  • Milazzo R; San Raffaele Telethon Institute for Gene Therapy, Division of Regenerative Medicine, Stem Cell and Gene Therapy, San Raffaele Scientific Institute, Milano, Italy.
  • Garcia-Manteiga JM; Centre for Translational Genomics and Bioinformatics, IRCCS San Raffaele Scientific Institute, Milano, Italy.
  • Cavalca E; San Raffaele Telethon Institute for Gene Therapy, Division of Regenerative Medicine, Stem Cell and Gene Therapy, San Raffaele Scientific Institute, Milano, Italy.
  • Montepeloso A; Gene Therapy Program, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA 02115, USA.
  • Garrison BS; San Raffaele Telethon Institute for Gene Therapy, Division of Regenerative Medicine, Stem Cell and Gene Therapy, San Raffaele Scientific Institute, Milano, Italy.
  • Peviani M; Gene Therapy Program, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA 02115, USA.
  • Rossi DJ; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA.
  • Biffi A; Program in Cellular and Molecular Medicine, Department of Medicine, Boston Children's Hospital, Boston, MA 02115, USA.
Sci Adv ; 3(12): e1701211, 2017 12.
Article em En | MEDLINE | ID: mdl-29226242
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ventrículos Cerebrais / Microglia / Transplante de Células-Tronco Hematopoéticas Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ventrículos Cerebrais / Microglia / Transplante de Células-Tronco Hematopoéticas Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article