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CDKN2A/p16 Deletion in Head and Neck Cancer Cells Is Associated with CDK2 Activation, Replication Stress, and Vulnerability to CHK1 Inhibition.
Gadhikar, Mayur A; Zhang, Jiexin; Shen, Li; Rao, Xiayu; Wang, Jing; Zhao, Mei; Kalu, Nene N; Johnson, Faye M; Byers, Lauren A; Heymach, John; Hittelman, Walter N; Udayakumar, Durga; Pandita, Raj K; Pandita, Tej K; Pickering, Curtis R; Redwood, Abena B; Piwnica-Worms, Helen; Schlacher, Katharina; Frederick, Mitchell J; Myers, Jeffrey N.
Afiliação
  • Gadhikar MA; Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Zhang J; Department of Biostatistics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Shen L; Department of Biostatistics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Rao X; Department of Biostatistics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Wang J; Department of Biostatistics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Zhao M; Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Kalu NN; Thoracic Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Johnson FM; Thoracic Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Byers LA; Thoracic Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Heymach J; Thoracic Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Hittelman WN; Department of Experimental Therapeutics, University of Texas, MD Anderson Cancer Center, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Udayakumar D; Department of Radiation Oncology, Institute for Academic Medicine, Houston Methodist, Houston, Texas.
  • Pandita RK; Department of Radiation Oncology, Institute for Academic Medicine, Houston Methodist, Houston, Texas.
  • Pandita TK; Department of Radiation Oncology, Institute for Academic Medicine, Houston Methodist, Houston, Texas.
  • Pickering CR; Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Redwood AB; Department of Experimental Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Piwnica-Worms H; Department of Experimental Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Schlacher K; Department of Cancer Biology, University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Frederick MJ; Department of Otolaryngology - Head and Neck Surgery, Baylor College of Medicine, Houston, Texas. jmyers@mdanderson.org Mitchell.Frederick@bcm.edu.
  • Myers JN; Department of Head and Neck Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas. jmyers@mdanderson.org Mitchell.Frederick@bcm.edu.
Cancer Res ; 78(3): 781-797, 2018 02 01.
Article em En | MEDLINE | ID: mdl-29229598
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Escamosas / Fase S / Inibidores Enzimáticos / Quinase 2 Dependente de Ciclina / Inibidor de Quinase Dependente de Ciclina p18 / Quinase 1 do Ponto de Checagem / Neoplasias de Cabeça e Pescoço Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Escamosas / Fase S / Inibidores Enzimáticos / Quinase 2 Dependente de Ciclina / Inibidor de Quinase Dependente de Ciclina p18 / Quinase 1 do Ponto de Checagem / Neoplasias de Cabeça e Pescoço Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article