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Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeutic strategy in cutaneous melanoma.
Wu, Chiao-En; Esfandiari, Arman; Ho, Yi-Hsuan; Wang, Nan; Mahdi, Ahmed Khairallah; Aptullahoglu, Erhan; Lovat, Penny; Lunec, John.
Afiliação
  • Wu CE; Northern Institute for Cancer Research, School of Medicine, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle-upon-Tyne NE2 4HH, UK.
  • Esfandiari A; Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan 333, Taiwan.
  • Ho YH; Northern Institute for Cancer Research, School of Medicine, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle-upon-Tyne NE2 4HH, UK.
  • Wang N; Northern Institute for Cancer Research, School of Medicine, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle-upon-Tyne NE2 4HH, UK.
  • Mahdi AK; Arraygen UK Ltd, Devonshire Building, Newcastle University, Newcastle-upon-Tyne NE1 7RU, UK.
  • Aptullahoglu E; Northern Institute for Cancer Research, School of Medicine, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle-upon-Tyne NE2 4HH, UK.
  • Lovat P; Department of Pathology and Forensic Medicine, College of Medicine, Al-Nahrain University, Baghdad 10006, Iraq.
  • Lunec J; Northern Institute for Cancer Research, School of Medicine, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle-upon-Tyne NE2 4HH, UK.
Br J Cancer ; 118(4): 495-508, 2018 02 20.
Article em En | MEDLINE | ID: mdl-29235570

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Mutagênese Sítio-Dirigida / Proteína Supressora de Tumor p53 / Dipeptídeos / Aminopiridinas / Melanoma Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Mutagênese Sítio-Dirigida / Proteína Supressora de Tumor p53 / Dipeptídeos / Aminopiridinas / Melanoma Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article