Evolution of a designed protein assembly encapsulating its own RNA genome.

Butterfield, Gabriel L; Lajoie, Marc J; Gustafson, Heather H; Sellers, Drew L; Nattermann, Una; Ellis, Daniel; Bale, Jacob B; Ke, Sharon; Lenz, Garreck H; Yehdego, Angelica; Ravichandran, Rashmi; Pun, Suzie H; King, Neil P; Baker, David

Butterfield, Gabriel L; Lajoie, Marc J; Gustafson, Heather H; Sellers, Drew L; Nattermann, Una; Ellis, Daniel; Bale, Jacob B; Ke, Sharon; Lenz, Garreck H; Yehdego, Angelica; Ravichandran, Rashmi; Pun, Suzie H; King, Neil P; Baker, David.

Afiliação

Butterfield GL; Institute for Protein Design, University of Washington, Seattle, Washington 98195, USA.
Lajoie MJ; Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA.
Gustafson HH; Graduate Program in Molecular and Cellular Biology, University of Washington, Seattle, Washington 98195, USA.
Sellers DL; Institute for Protein Design, University of Washington, Seattle, Washington 98195, USA.
Nattermann U; Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA.
Ellis D; Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA.
Bale JB; Molecular Engineering and Sciences Institute, University of Washington, Seattle, Washington 98195, USA.
Ke S; Department of Bioengineering, University of Washington, Seattle, Washington 98195, USA.
Lenz GH; Molecular Engineering and Sciences Institute, University of Washington, Seattle, Washington 98195, USA.
Yehdego A; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington 98109, USA.
Ravichandran R; Institute for Protein Design, University of Washington, Seattle, Washington 98195, USA.
Pun SH; Department of Biochemistry, University of Washington, Seattle, Washington 98195, USA.
King NP; Graduate Program in Biological Physics, Structure & Design, University of Washington, Seattle, Washington 98195, USA.
Baker D; Institute for Protein Design, University of Washington, Seattle, Washington 98195, USA.

Nature ; 552(7685): 415-420, 2017 12 21.

Article em En | MEDLINE | ID: mdl-29236688

Assuntos

Bioengenharia; Evolução Molecular Direcionada; Genoma Viral; Nucleocapsídeo/genética; Nucleocapsídeo/metabolismo; RNA Viral/metabolismo; Montagem de Vírus; Animais; Sistemas de Liberação de Medicamentos; Escherichia coli/genética; Escherichia coli/metabolismo; Feminino; Produtos do Gene tat/genética; Produtos do Gene tat/metabolismo; Aptidão Genética; Terapia Genética; Vírus da Imunodeficiência Bovina/química; Vírus da Imunodeficiência Bovina/genética; Camundongos; Modelos Moleculares; Nucleocapsídeo/química; RNA Mensageiro/metabolismo; Seleção Genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Viral / Genoma Viral / Montagem de Vírus / Evolução Molecular Direcionada / Nucleocapsídeo / Bioengenharia Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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