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Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers.
Sanchez, Gilson J; Richmond, Phillip A; Bunker, Eric N; Karman, Samuel S; Azofeifa, Joseph; Garnett, Aaron T; Xu, Quanbin; Wheeler, Graycen E; Toomey, Cathryn M; Zhang, Qinghong; Dowell, Robin D; Liu, Xuedong.
Afiliação
  • Sanchez GJ; Department of Chemistry and Biochemistry, University of Colorado-Boulder, Boulder, CO 80309, USA.
  • Richmond PA; BioFrontiers Institute and IQ Biology Program, University of Colorado-Boulder, Boulder, CO 80303, USA.
  • Bunker EN; Molecular, Cellular, and Developmental Biology, University of Colorado-Boulder, Boulder, CO 80309, USA.
  • Karman SS; Department of Chemistry and Biochemistry, University of Colorado-Boulder, Boulder, CO 80309, USA.
  • Azofeifa J; Department of Chemistry and Biochemistry, University of Colorado-Boulder, Boulder, CO 80309, USA.
  • Garnett AT; BioFrontiers Institute and IQ Biology Program, University of Colorado-Boulder, Boulder, CO 80303, USA.
  • Xu Q; Ecology and Evolutionary Biology, University of Colorado-Boulder, Boulder, CO 80309, USA.
  • Wheeler GE; Department of Chemistry and Biochemistry, University of Colorado-Boulder, Boulder, CO 80309, USA.
  • Toomey CM; Department of Chemistry and Biochemistry, University of Colorado-Boulder, Boulder, CO 80309, USA.
  • Zhang Q; Department of Chemistry and Biochemistry, University of Colorado-Boulder, Boulder, CO 80309, USA.
  • Dowell RD; Department of Dermatology, University of Colorado Denver, Aurora, CO 80045, USA.
  • Liu X; BioFrontiers Institute and IQ Biology Program, University of Colorado-Boulder, Boulder, CO 80303, USA.
Nucleic Acids Res ; 46(4): 1756-1776, 2018 02 28.
Article em En | MEDLINE | ID: mdl-29240919
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiazóis / Elementos Facilitadores Genéticos / Código das Histonas / Depsipeptídeos / Inibidores de Histona Desacetilases Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiazóis / Elementos Facilitadores Genéticos / Código das Histonas / Depsipeptídeos / Inibidores de Histona Desacetilases Idioma: En Ano de publicação: 2018 Tipo de documento: Article