The Candida species that are important for the development of atrophic glossitis in xerostomia patients.
BMC Oral Health
; 17(1): 153, 2017 Dec 16.
Article
em En
| MEDLINE
| ID: mdl-29246167
ABSTRACT
BACKGROUND:
The purpose of this study was to clarify the species of Candida that are important for the development of atrophic glossitis in xerostomia patients.METHODS:
A total of 231 patients with subjective dry mouth were enrolled in the present study. Logistic regression analysis was performed to clarify the contribution of each Candida species and other variables to the development of atrophic glossitis. The dependent variable was the absence/presence of atrophic glossitis. The Candida colony-forming units (CFU) of C. albicans, C. glabrata, C. tropicalis, and C. krusei, as well as age, gender, resting (RSFR) and stimulated (SSFR) whole salivary flow rate, and denture-wearing status, were treated as explanatory variables.RESULTS:
Logistic regression analysis showed that two factors were closely associated with the presence of atrophic glossitis an increase in C. albicans CFU and a decrease in the SSFR.CONCLUSIONS:
C. albicans, but not non-albicans Candida, was associated with atrophic glossitis in xerostomia patients who had no systemic predisposing factors, indicating that C. albicans remains a treatment target for Candida-related atrophic glossitis.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Língua
/
Xerostomia
/
Candida
/
Candida albicans
/
Candidíase
/
Glossite
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
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Aged80
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article