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Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome) Complicated by Perforation of the Small Intestine and Cholecystitis.
Ohnuki, Yoichi; Moriya, Yusuke; Yutani, Sachiko; Mizuma, Atsushi; Nakayama, Taira; Ohnuki, Yuko; Uda, Shuji; Inomoto, Chie; Yamamoto, Soichiro; Nakamura, Naoya; Takizawa, Shunya.
Afiliação
  • Ohnuki Y; Division of Neurology, Department of Internal Medicine, Tokai University School of Medicine, Japan.
  • Moriya Y; Division of Neurology, Department of Internal Medicine, Tokai University School of Medicine, Japan.
  • Yutani S; Division of Neurology, Department of Internal Medicine, Tokai University School of Medicine, Japan.
  • Mizuma A; Division of Neurology, Department of Internal Medicine, Tokai University School of Medicine, Japan.
  • Nakayama T; Division of Neurology, Department of Internal Medicine, Tokai University School of Medicine, Japan.
  • Ohnuki Y; Department of Molecular Life Science Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Japan.
  • Uda S; Department of Gastroenterological Surgery, Tokai University School of Medicine, Japan.
  • Inomoto C; Department of Pathology, Tokai University School of Medicine, Japan.
  • Yamamoto S; Department of Gastroenterological Surgery, Tokai University School of Medicine, Japan.
  • Nakamura N; Department of Pathology, Tokai University School of Medicine, Japan.
  • Takizawa S; Division of Neurology, Department of Internal Medicine, Tokai University School of Medicine, Japan.
Intern Med ; 57(5): 737-740, 2018 Mar 01.
Article em En | MEDLINE | ID: mdl-29269641
We report a case of eosinophilic granulomatosis with polyangiitis (EGPA; formerly known as Churg-Strauss syndrome) complicated by perforation of the small intestine and necrotizing cholecystitis. A 69-year-old man with a history of bronchial asthma was admitted with mononeuritis multiplex. The laboratory findings included remarkable eosinophilia. He was treated with corticosteroids and his laboratory indices showed improvement; however, his functional deficits remained. His neuropathy gradually improved after the addition of intravenous immunoglobulin (IVIG). He was subsequently treated with oral prednisolone (40 mg/day) as maintenance therapy. Within a month after finishing IVIG, he developed perforation of the small intestine and necrotizing cholecystitis. Intestinal perforation has often been reported as a gastrointestinal complication of EGPA. In contrast, cholecystitis is a rare complication. We report this case because the manifestation of more than one complication is extremely rare. Gastrointestinal symptoms may be a complication of EGPA itself and/or immunosuppressive treatment.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Granulomatose com Poliangiite / Colecistite / Perfuração Intestinal / Intestino Delgado Tipo de estudo: Etiology_studies Limite: Aged / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Granulomatose com Poliangiite / Colecistite / Perfuração Intestinal / Intestino Delgado Tipo de estudo: Etiology_studies Limite: Aged / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article