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Leukoerythroblastosis in a Young Child with Severe Malaria and Superimposed Gram Negative Infection.
Varo, Rosauro; Sitoe, Antonio; Cossa, Anelsio; Ordi, Jaume; Rozman, Maria; Bassat, Quique.
Afiliação
  • Varo R; Centro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.
  • Sitoe A; ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic - Universitat de Barcelona, Barcelona 08036, Spain.
  • Cossa A; Centro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.
  • Ordi J; Centro de Investigação em Saúde de Manhiça (CISM), Maputo 1929, Mozambique.
  • Rozman M; ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic - Universitat de Barcelona, Barcelona 08036, Spain.
  • Bassat Q; Department of Pathology, Hospital Clinic of Barcelona, Universitat de Barcelona, Barcelona 08036, Spain.
J Trop Pediatr ; 64(6): 553-556, 2018 12 01.
Article em En | MEDLINE | ID: mdl-29272534
ABSTRACT

Background:

Leukoerythroblastosis, a non-specific and often short-lasting response of the bone marrow to different diseases such as malignancies or infections, is characterized by the presence in the peripheral blood of immature red and white cells.

Methods:

We present a case of leukoerythoblastosis occurring in a 24 months old Mozambican girl, in the context of a severe malaria episode and an associated urinary tract infection. Peripheral blood smear was used for diagnosis of malaria and leukoerythroblastosis. Enterobacter cloacae isolation and antibiotic susceptibility testing were performed by conventional microbiology.

Results:

Peripheral blood smear was positive for Plasmodium falciparum and showed a leukoerythroblastosis with red cell anisopoikilocytosis and left shifted neutrophils. Urine culture confirmed the presence of a multi-resistant E. cloacae. Treatment of underlying conditions resolved the leukoerythroblastic reaction.

Conclusions:

Leukoerythroblastosis may be related to different infectious diseases and may also appear in the context of severe malaria. Bacterial superinfection needs to be investigated.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Infecções Urinárias / Malária Falciparum / Enterobacter cloacae / Infecções por Enterobacteriaceae / Anemia Mielopática Tipo de estudo: Diagnostic_studies Limite: Child, preschool / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Infecções Urinárias / Malária Falciparum / Enterobacter cloacae / Infecções por Enterobacteriaceae / Anemia Mielopática Tipo de estudo: Diagnostic_studies Limite: Child, preschool / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article