<i>Listeria monocytogenes</i> triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy.

Mitchell, Gabriel; Cheng, Mandy I; Chen, Chen; Nguyen, Brittney N; Whiteley, Aaron T; Kianian, Sara; Cox, Jeffery S; Green, Douglas R; McDonald, Kent L; Portnoy, Daniel A

Listeria monocytogenes triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy.

Mitchell, Gabriel; Cheng, Mandy I; Chen, Chen; Nguyen, Brittney N; Whiteley, Aaron T; Kianian, Sara; Cox, Jeffery S; Green, Douglas R; McDonald, Kent L; Portnoy, Daniel A.

Afiliação

Mitchell G; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.
Cheng MI; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.
Chen C; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.
Nguyen BN; Graduate Group in Microbiology, University of California, Berkeley, CA 94720.
Whiteley AT; Graduate Group in Infectious Diseases and Immunity, School of Public Health, University of California, Berkeley, CA 94720.
Kianian S; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.
Cox JS; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720.
Green DR; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105.
McDonald KL; Electron Microscope Laboratory, University of California, Berkeley, CA 94720.
Portnoy DA; Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720; portnoy@berkeley.edu.

Proc Natl Acad Sci U S A ; 115(2): E210-E217, 2018 01 09.

Article em En | MEDLINE | ID: mdl-29279409

Assuntos

Autofagia; Listeria monocytogenes/fisiologia; Macrófagos/microbiologia; Fagocitose; Animais; Proteínas de Bactérias/genética; Proteínas de Bactérias/metabolismo; Células Cultivadas; Citosol/metabolismo; Citosol/microbiologia; Interações Hospedeiro-Patógeno; Listeria monocytogenes/genética; Macrófagos/metabolismo; Proteínas de Membrana/genética; Proteínas de Membrana/metabolismo; Camundongos Knockout; Camundongos Transgênicos; Microscopia de Fluorescência; Mutação; Fagossomos/metabolismo; Fagossomos/microbiologia; Imagem com Lapso de Tempo/métodos; Fosfolipases Tipo C/genética; Fosfolipases Tipo C/metabolismo

Palavras-chave

ActA; LC3-associated phagocytosis; bacteria; macrophage; phospholipases

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fagocitose / Autofagia / Listeria monocytogenes / Macrófagos Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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