Toll-Like Receptor 2-Mediated Glial Cell Activation in a Mouse Model of Cuprizone-Induced Demyelination.

Esser, Stefan; Göpfrich, Larissa; Bihler, Kai; Kress, Eugenia; Nyamoya, Stella; Tauber, Simone C; Clarner, Tim; Stope, Matthias B; Pufe, Thomas; Kipp, Markus; Brandenburg, Lars-Ove

Esser, Stefan; Göpfrich, Larissa; Bihler, Kai; Kress, Eugenia; Nyamoya, Stella; Tauber, Simone C; Clarner, Tim; Stope, Matthias B; Pufe, Thomas; Kipp, Markus; Brandenburg, Lars-Ove.

Afiliação

Esser S; Department of Anatomy and Cell Biology, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany.
Göpfrich L; Department of Anatomy and Cell Biology, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany.
Bihler K; Department of Anatomy and Cell Biology, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany.
Kress E; Department of Anatomy and Cell Biology, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany.
Nyamoya S; Institute of Neuroanatomy, RWTH Aachen University, Aachen, Germany.
Tauber SC; Department of Neurology, RWTH University Hospital Aachen, Aachen, Germany.
Clarner T; Institute of Neuroanatomy, RWTH Aachen University, Aachen, Germany.
Stope MB; Department of Urology, University Medicine Greifswald, Greifswald, Germany.
Pufe T; Department of Anatomy and Cell Biology, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany.
Kipp M; Department of Anatomy II, Ludwig-Maximilians-University of Munich, Munich, Germany.
Brandenburg LO; Department of Anatomy and Cell Biology, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany. lbrandenburg@ukaachen.de.

Mol Neurobiol ; 55(8): 6237-6249, 2018 Aug.

Article em En | MEDLINE | ID: mdl-29288338

Assuntos

Doenças Desmielinizantes/metabolismo; Neuroglia/metabolismo; Receptor 2 Toll-Like/metabolismo; Animais; Astrócitos/metabolismo; Astrócitos/patologia; Corpo Caloso/metabolismo; Corpo Caloso/patologia; Cuprizona; Doenças Desmielinizantes/induzido quimicamente; Doenças Desmielinizantes/genética; Doenças Desmielinizantes/patologia; Modelos Animais de Doenças; Hipocampo/metabolismo; Hipocampo/patologia; Contagem de Linfócitos; Linfócitos/patologia; Camundongos Endogâmicos C57BL; Microglia/metabolismo; Microglia/patologia; Oligodendroglia/metabolismo; Oligodendroglia/patologia; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Receptor 2 Toll-Like/deficiência; Receptor 2 Toll-Like/genética

Palavras-chave

CNS; Cuprizone; Demyelination; Multiple sclerosis; Pattern recognition receptor; Toll-like receptor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neuroglia / Doenças Desmielinizantes / Receptor 2 Toll-Like Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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