Effects of Moisture-Induced Crystallization on the Aerosol Performance of Spray Dried Amorphous Ciprofloxacin Powder Formulations.

Shetty, Nivedita; Zeng, Lingfei; Mangal, Sharad; Nie, Haichen; Rowles, Matthew R; Guo, Rui; Han, Youngwoo; Park, Joon Hyeong; Zhou, Qi Tony

Shetty, Nivedita; Zeng, Lingfei; Mangal, Sharad; Nie, Haichen; Rowles, Matthew R; Guo, Rui; Han, Youngwoo; Park, Joon Hyeong; Zhou, Qi Tony.

Afiliação

Shetty N; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana, 47907, USA.
Zeng L; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana, 47907, USA.
Mangal S; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana, 47907, USA.
Nie H; Teva Pharmaceuticals, 145 Brandywine Pkwy, West Chester, Pennsylvania, 19380, USA.
Rowles MR; Department of Physics and Astronomy, Curtin University, Bentley, WA, 6102, Australia.
Guo R; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana, 47907, USA.
Han Y; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana, 47907, USA.
Park JH; Birck Nanotechnology Center, Purdue University, 1205 West State Street, West Lafayette, Indiana, 47907, USA.
Zhou QT; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana, 47907, USA. tonyzhou@purdue.edu.

Pharm Res ; 35(1): 7, 2018 01 02.

Article em En | MEDLINE | ID: mdl-29294198

Assuntos

Aerossóis/química; Cristalização/métodos; Composição de Medicamentos/métodos; Pós/química; Vapor; Administração por Inalação; Varredura Diferencial de Calorimetria; Cromatografia Líquida de Alta Pressão/métodos; Ciprofloxacina; Humanos; Umidade; Cinética; Microscopia de Força Atômica/métodos; Microscopia Eletrônica de Varredura/métodos; Tamanho da Partícula; Propriedades de Superfície; Difração de Raios X/métodos

Palavras-chave

aerosol performance; amorphous powder; crystallization; dry powder inhaler; particle surface roughness; spray drying; storage humidity

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pós / Vapor / Aerossóis / Cristalização / Composição de Medicamentos Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google