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Rational Design of a New Class of Toll-Like Receptor 4 (TLR4) Tryptamine Related Agonists by Means of the Structure- and Ligand-Based Virtual Screening for Vaccine Adjuvant Discovery.
Honegr, Jan; Dolezal, Rafael; Malinak, David; Benkova, Marketa; Soukup, Ondrej; Almeida, Joyce S F D de; Franca, Tanos C C; Kuca, Kamil; Prymula, Roman.
Afiliação
  • Honegr J; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 50005 Hradec Kralove, Czech Republic. jan.honegr@gmail.com.
  • Dolezal R; Department of Forensic Medicine and Intensive Medicine, Faculty of Medicine, University of Ostrava, Syllabova 19, Ostrava 70300, Czech Republic. jan.honegr@gmail.com.
  • Malinak D; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 50005 Hradec Kralove, Czech Republic. rafael.dolezal@fnhk.cz.
  • Benkova M; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanskeho 62, 50003 Hradec Kralove, Czech Republic. rafael.dolezal@fnhk.cz.
  • Soukup O; Center for Basic and Applied Research, Faculty of Informatics and Management, University of Hradec Kralove, Rokitanskeho 62, 50003 Hradec Kralove, Czech Republic. rafael.dolezal@fnhk.cz.
  • Almeida JSFD; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 50005 Hradec Kralove, Czech Republic. david.malinak@gmail.com.
  • Franca TCC; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanskeho 62, 50003 Hradec Kralove, Czech Republic. david.malinak@gmail.com.
  • Kuca K; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 50005 Hradec Kralove, Czech Republic. marketa.pasdiorova@fnhk.cz.
  • Prymula R; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 50005 Hradec Kralove, Czech Republic. ondrej.soukup@fnhk.cz.
Molecules ; 23(1)2018 Jan 04.
Article em En | MEDLINE | ID: mdl-29300367
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Relação Estrutura-Atividade / Adjuvantes Imunológicos / Receptor 4 Toll-Like / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Relação Estrutura-Atividade / Adjuvantes Imunológicos / Receptor 4 Toll-Like / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article