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Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors.
Kalin, Jay H; Wu, Muzhou; Gomez, Andrea V; Song, Yun; Das, Jayanta; Hayward, Dawn; Adejola, Nkosi; Wu, Mingxuan; Panova, Izabela; Chung, Hye Jin; Kim, Edward; Roberts, Holly J; Roberts, Justin M; Prusevich, Polina; Jeliazkov, Jeliazko R; Roy Burman, Shourya S; Fairall, Louise; Milano, Charles; Eroglu, Abdulkerim; Proby, Charlotte M; Dinkova-Kostova, Albena T; Hancock, Wayne W; Gray, Jeffrey J; Bradner, James E; Valente, Sergio; Mai, Antonello; Anders, Nicole M; Rudek, Michelle A; Hu, Yong; Ryu, Byungwoo; Schwabe, John W R; Mattevi, Andrea; Alani, Rhoda M; Cole, Philip A.
Afiliação
  • Kalin JH; Division of Genetics, Departments of Medicine and Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, 02115, USA.
  • Wu M; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Gomez AV; Department of Dermatology, Boston University School of Medicine, Boston, MA, 02118, USA.
  • Song Y; Department of Biology and Biotechnology, University of Pavia, 27100, Pavia, Italy.
  • Das J; Department of Molecular and Cell Biology, University of Leicester, Leicester, LE1 9HN, UK.
  • Hayward D; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Adejola N; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Wu M; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Panova I; Division of Genetics, Departments of Medicine and Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, 02115, USA.
  • Chung HJ; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Kim E; Department of Dermatology, Boston University School of Medicine, Boston, MA, 02118, USA.
  • Roberts HJ; Department of Dermatology, Boston University School of Medicine, Boston, MA, 02118, USA.
  • Roberts JM; Department of Dermatology, Boston University School of Medicine, Boston, MA, 02118, USA.
  • Prusevich P; Department of Dermatology, Boston University School of Medicine, Boston, MA, 02118, USA.
  • Jeliazkov JR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Roy Burman SS; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Fairall L; Program in Molecular Biophysics, Johns Hopkins University, Baltimore, MD, 21218, USA.
  • Milano C; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
  • Eroglu A; Department of Molecular and Cell Biology, University of Leicester, Leicester, LE1 9HN, UK.
  • Proby CM; Department of Molecular and Cell Biology, University of Leicester, Leicester, LE1 9HN, UK.
  • Dinkova-Kostova AT; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Hancock WW; Division of Cancer Research, Jacqui Wood Cancer Centre, University of Dundee, Dundee, DD1 9SY, UK.
  • Gray JJ; Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Bradner JE; Division of Cancer Research, Jacqui Wood Cancer Centre, University of Dundee, Dundee, DD1 9SY, UK.
  • Valente S; Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.
  • Mai A; Program in Molecular Biophysics, Johns Hopkins University, Baltimore, MD, 21218, USA.
  • Anders NM; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
  • Rudek MA; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Hu Y; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
  • Ryu B; Pasteur Institute, Cenci-Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, 00185, Rome, Italy.
  • Schwabe JWR; Pasteur Institute, Cenci-Bolognetti Foundation, Department of Drug Chemistry and Technologies, Sapienza University of Rome, 00185, Rome, Italy.
  • Mattevi A; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Alani RM; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
  • Cole PA; Department of Oncology, BioDuro LLC, Shanghai, 200131, China.
Nat Commun ; 9(1): 53, 2018 01 04.
Article em En | MEDLINE | ID: mdl-29302039
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Tranilcipromina / Benzamidas / Proteínas Correpressoras / Inibidores de Histona Desacetilases / Melanoma / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Tranilcipromina / Benzamidas / Proteínas Correpressoras / Inibidores de Histona Desacetilases / Melanoma / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article