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The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells ex vivo but fails to prevent leukemia development in a murine model.
Wierz, Marina; Pierson, Sandrine; Chouha, Nora; Désaubry, Laurent; François, Jean-Hugues; Berchem, Guy; Paggetti, Jerome; Moussay, Etienne.
Afiliação
  • Wierz M; Laboratory of Experimental Cancer Research, Department of Oncology, Luxembourg Institute of Health, Luxembourg.
  • Pierson S; Laboratory of Experimental Cancer Research, Department of Oncology, Luxembourg Institute of Health, Luxembourg.
  • Chouha N; Laboratory of Therapeutic Innovation (UMR 7200) CNRS/Université de Strasbourg, Faculté de Pharmacie, Illkirch, Luxembourg.
  • Désaubry L; Laboratory of Therapeutic Innovation (UMR 7200) CNRS/Université de Strasbourg, Faculté de Pharmacie, Illkirch, Luxembourg.
  • François JH; Centre Hospitalier de Luxembourg, Luxembourg.
  • Berchem G; Laboratory of Experimental Cancer Research, Department of Oncology, Luxembourg Institute of Health, Luxembourg.
  • Paggetti J; Centre Hospitalier de Luxembourg, Luxembourg.
  • Moussay E; Laboratory of Experimental Cancer Research, Department of Oncology, Luxembourg Institute of Health, Luxembourg jerome.paggetti@lih.lu etienne.moussay@lih.lu.
Haematologica ; 103(4): e154-e157, 2018 04.
Article em En | MEDLINE | ID: mdl-29305413
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Tiazóis / Leucemia Linfocítica Crônica de Células B / Apoptose Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Tiazóis / Leucemia Linfocítica Crônica de Células B / Apoptose Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article