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Tailoring Mathematical Models to Stem-Cell Derived Cardiomyocyte Lines Can Improve Predictions of Drug-Induced Changes to Their Electrophysiology.
Lei, Chon Lok; Wang, Ken; Clerx, Michael; Johnstone, Ross H; Hortigon-Vinagre, Maria P; Zamora, Victor; Allan, Andrew; Smith, Godfrey L; Gavaghan, David J; Mirams, Gary R; Polonchuk, Liudmila.
Afiliação
  • Lei CL; Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom.
  • Wang K; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
  • Clerx M; Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom.
  • Johnstone RH; Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom.
  • Hortigon-Vinagre MP; Clyde Biosciences, BioCity Scotland, Newhouse, United Kingdom.
  • Zamora V; Clyde Biosciences, BioCity Scotland, Newhouse, United Kingdom.
  • Allan A; Clyde Biosciences, BioCity Scotland, Newhouse, United Kingdom.
  • Smith GL; Clyde Biosciences, BioCity Scotland, Newhouse, United Kingdom.
  • Gavaghan DJ; Computational Biology, Department of Computer Science, University of Oxford, Oxford, United Kingdom.
  • Mirams GR; Centre for Mathematical Medicine and Biology, School of Mathematical Sciences, University of Nottingham, Nottingham, United Kingdom.
  • Polonchuk L; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
Front Physiol ; 8: 986, 2017.
Article em En | MEDLINE | ID: mdl-29311950
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2017 Tipo de documento: Article