Coxsackievirus and Type 1 Diabetes Mellitus: The Wolf's Footprints.

Eizirik, Decio L; Op de Beeck, Anne

Eizirik, Decio L; Op de Beeck, Anne.

Afiliação

Eizirik DL; ULB Center for Diabetes Research, Université Libre de Bruxelles, Brussels, Belgium. Electronic address: deizirik@ulb.ac.be.
Op de Beeck A; ULB Center for Diabetes Research, Université Libre de Bruxelles, Brussels, Belgium. Electronic address: Anne.Op.De.Beeck@ulb.ac.be.

Trends Endocrinol Metab ; 29(3): 137-139, 2018 03.

Article em En | MEDLINE | ID: mdl-29326001

ABSTRACT

ABSTRACT

Enteroviruses are important environmental contributors to islet inflammation (insulitis) in type 1 diabetes mellitus (T1DM). A recent study characterized the proteomic alterations induced by Coxsackievirus type B (CVB) infection of human islets. This provides relevant information to decipher the words of the virus-induced 'dialog' between ß cells and the immune system that leads to autoimmunity.

Assuntos

Infecções por Coxsackievirus/imunologia; Diabetes Mellitus Tipo 1/imunologia; Ilhotas Pancreáticas/imunologia; Humanos; Proteômica

Palavras-chave

coxsackievirus; diabetes mellitus; insulitis; pancreatic beta cells; pancreatic islets

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ilhotas Pancreáticas / Infecções por Coxsackievirus / Diabetes Mellitus Tipo 1 Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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