A biosensor-based framework to measure latent proteostasis capacity.

Wood, Rebecca J; Ormsby, Angelique R; Radwan, Mona; Cox, Dezerae; Sharma, Abhishek; Vöpel, Tobias; Ebbinghaus, Simon; Oliveberg, Mikael; Reid, Gavin E; Dickson, Alex; Hatters, Danny M

Wood, Rebecca J; Ormsby, Angelique R; Radwan, Mona; Cox, Dezerae; Sharma, Abhishek; Vöpel, Tobias; Ebbinghaus, Simon; Oliveberg, Mikael; Reid, Gavin E; Dickson, Alex; Hatters, Danny M.

Afiliação

Wood RJ; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, 3010, Australia.
Ormsby AR; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, 3010, Australia.
Radwan M; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, 3010, Australia.
Cox D; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, 3010, Australia.
Sharma A; Department of Physical Chemistry II, Ruhr-University Bochum, Universitaetsstraße 150, 44780, Bochum, Germany.
Vöpel T; Department of Physical Chemistry II, Ruhr-University Bochum, Universitaetsstraße 150, 44780, Bochum, Germany.
Ebbinghaus S; Department of Physical Chemistry II, Ruhr-University Bochum, Universitaetsstraße 150, 44780, Bochum, Germany.
Oliveberg M; Department of Biochemistry and Biophysics, Arrhenius Laboratories of Natural Sciences, Stockholm University, 10691, Stockholm, Sweden.
Reid GE; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, 3010, Australia.
Dickson A; School of Chemistry, University of Melbourne, Parkville, VIC, 3010, Australia.
Hatters DM; Department of Biochemistry & Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA.

Nat Commun ; 9(1): 287, 2018 01 18.

Article em En | MEDLINE | ID: mdl-29348634

Assuntos

Técnicas Biossensoriais/métodos; Citometria de Fluxo/métodos; Modelos Teóricos; Proteostase; Algoritmos; Western Blotting; Células HEK293; Proteínas de Choque Térmico HSP72/metabolismo; Proteínas de Choque Térmico HSP90/metabolismo; Fatores de Transcrição de Choque Térmico/metabolismo; Humanos; Proteoma/metabolismo; Proteômica/métodos; Espectrometria de Massas em Tandem/métodos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Citometria de Fluxo / Proteostase / Modelos Teóricos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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