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Natural Killer Cell-Based Immunotherapy in Gynecologic Malignancy: A Review.
Uppendahl, Locke D; Dahl, Carly M; Miller, Jeffrey S; Felices, Martin; Geller, Melissa A.
Afiliação
  • Uppendahl LD; Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota School of Medicine, Minneapolis, MN, United States.
  • Dahl CM; University of Minnesota School of Medicine, Minneapolis, MN, United States.
  • Miller JS; Department of Medicine, Division of Hematology, Oncology, and Transplantation, University of Minnesota School of Medicine, Minneapolis, MN, United States.
  • Felices M; Department of Medicine, Division of Hematology, Oncology, and Transplantation, University of Minnesota School of Medicine, Minneapolis, MN, United States.
  • Geller MA; Department of Obstetrics, Gynecology and Women's Health, Division of Gynecologic Oncology, University of Minnesota School of Medicine, Minneapolis, MN, United States.
Front Immunol ; 8: 1825, 2017.
Article em En | MEDLINE | ID: mdl-29354116
ABSTRACT
Harnessing the immune system has proven an effective therapy in treating malignancies. Since the discovery of natural killer (NK) cells, strategies aimed to manipulate and augment their effector function against cancer have been the subject of intense research. Recent progress in the immunobiology of NK cells has led to the development of promising therapeutic approaches. In this review, we will focus on the recent advances in NK cell immunobiology and the clinical application of NK cell immunotherapy in ovarian, cervical, and uterine cancer.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2017 Tipo de documento: Article