The glycosomal alkyl-dihydroxyacetonephosphate synthase TbADS is essential for the synthesis of ether glycerophospholipids in procyclic trypanosomes.

Lee, Sungsu; Cheung-See-Kit, Melanie; Williams, Tyler A; Yamout, Nader; Zufferey, Rachel

Lee, Sungsu; Cheung-See-Kit, Melanie; Williams, Tyler A; Yamout, Nader; Zufferey, Rachel.

Afiliação

Lee S; Department of Biological Sciences, St John's University, 8000 Utopia Parkway, Jamaica, NY 11439, USA.
Cheung-See-Kit M; Department of Biological Sciences, St John's University, 8000 Utopia Parkway, Jamaica, NY 11439, USA.
Williams TA; Department of Biological Sciences, St John's University, 8000 Utopia Parkway, Jamaica, NY 11439, USA.
Yamout N; Department of Biological Sciences, St John's University, 8000 Utopia Parkway, Jamaica, NY 11439, USA.
Zufferey R; Department of Biological Sciences, St John's University, 8000 Utopia Parkway, Jamaica, NY 11439, USA. Electronic address: zufferer@stjohns.edu.

Exp Parasitol ; 185: 71-78, 2018 Feb.

Article em En | MEDLINE | ID: mdl-29355496

Assuntos

Alquil e Aril Transferases/metabolismo; Glicerofosfolipídeos/biossíntese; Leishmania major/enzimologia; Microcorpos/enzimologia; Trypanosoma brucei brucei/enzimologia; Leishmania major/genética; Leishmania major/metabolismo; Mutação com Perda de Função; Plasmídeos/química; Plasmídeos/genética; Plasmídeos/metabolismo; Espectrometria de Massas em Tandem; Trypanosoma brucei brucei/metabolismo

Palavras-chave

Alkyl-dihydroxyacetonephosphate synthase; Ether glycerophospholipids; Glycosome; Null mutant; Trypanosoma brucei

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trypanosoma brucei brucei / Leishmania major / Alquil e Aril Transferases / Glicerofosfolipídeos / Microcorpos Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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