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Lipidomics unveils the complexity of the lipidome in metabolic diseases.
Lydic, Todd A; Goo, Young-Hwa.
Afiliação
  • Lydic TA; Department of Physiology, Michigan State University, East Lansing, MI, 48824, USA. lydictod@msu.edu.
  • Goo YH; Department of Molecular and Cellular Physiology, Albany Medical College, 47 New Scotland Avenue, Albany, NY, 12208, USA. gooy@amc.edu.
Clin Transl Med ; 7(1): 4, 2018 Jan 26.
Article em En | MEDLINE | ID: mdl-29374337
Dysregulation of lipid metabolism is responsible for pathologies of human diseases including metabolic diseases. Recent advances in lipidomics analysis allow for the targeted and untargeted identification of lipid species and for their quantification in normal and diseased conditions. Herein, this review provides a brief introduction to lipidomics, highlights its application to characterize the lipidome at the cellular and physiological levels under different biological conditions, and discusses the potential for the use of lipidomics in the discovery of biomarkers.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article