Streptococcus pneumoniae PspC Subgroup Prevalence in Invasive Disease and Differences in Contribution to Complement Evasion.

van der Maten, Erika; van den Broek, Bryan; de Jonge, Marien I; Rensen, Kim J W; Eleveld, Marc J; Zomer, Aldert L; Cremers, Amelieke J H; Ferwerda, Gerben; de Groot, Ronald; Langereis, Jeroen D; van der Flier, Michiel

van der Maten, Erika; van den Broek, Bryan; de Jonge, Marien I; Rensen, Kim J W; Eleveld, Marc J; Zomer, Aldert L; Cremers, Amelieke J H; Ferwerda, Gerben; de Groot, Ronald; Langereis, Jeroen D; van der Flier, Michiel.

Afiliação

van der Maten E; Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
van den Broek B; Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
de Jonge MI; Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Rensen KJW; Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Eleveld MJ; Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Zomer AL; Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Cremers AJH; Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Ferwerda G; Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
de Groot R; Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Langereis JD; Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
van der Flier M; Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands michiel.vanderflier@radboudumc.nl.

Infect Immun ; 86(4)2018 04.

Article em En | MEDLINE | ID: mdl-29378798

Assuntos

Proteínas de Bactérias/genética; Proteínas de Bactérias/imunologia; Proteínas do Sistema Complemento/imunologia; Genótipo; Infecções Pneumocócicas/imunologia; Infecções Pneumocócicas/microbiologia; Streptococcus pneumoniae/genética; Streptococcus pneumoniae/imunologia; Idoso; Fator H do Complemento/imunologia; Fator H do Complemento/metabolismo; Proteínas do Sistema Complemento/metabolismo; Feminino; Humanos; Evasão da Resposta Imune; Masculino; Pessoa de Meia-Idade; Tipagem Molecular; Mutação; Infecções Pneumocócicas/epidemiologia; Prevalência; Sorogrupo; Virulência/genética; Fatores de Virulência/genética

Palavras-chave

PspC; Streptococcus pneumoniae; complement; factor H; immune evasion; invasive disease

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Pneumocócicas / Streptococcus pneumoniae / Proteínas de Bactérias / Proteínas do Sistema Complemento / Genótipo Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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