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Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly.
Aramillo Irizar, Peer; Schäuble, Sascha; Esser, Daniela; Groth, Marco; Frahm, Christiane; Priebe, Steffen; Baumgart, Mario; Hartmann, Nils; Marthandan, Shiva; Menzel, Uwe; Müller, Jule; Schmidt, Silvio; Ast, Volker; Caliebe, Amke; König, Rainer; Krawczak, Michael; Ristow, Michael; Schuster, Stefan; Cellerino, Alessandro; Diekmann, Stephan; Englert, Christoph; Hemmerich, Peter; Sühnel, Jürgen; Guthke, Reinhard; Witte, Otto W; Platzer, Matthias; Ruppin, Eytan; Kaleta, Christoph.
Afiliação
  • Aramillo Irizar P; Research Group Medical Systems Biology, Institute of Experimental Medicine, Christian-Albrechts-University Kiel, D-24105, Kiel, Germany.
  • Schäuble S; Jena University Language and Information Engineering Lab, Friedrich-Schiller-University Jena, D-07743, Jena, Germany.
  • Esser D; GerontoSys JenAge Consortium, D-07745, Jena, Germany.
  • Groth M; Research Group Medical Systems Biology, Institute of Experimental Medicine, Christian-Albrechts-University Kiel, D-24105, Kiel, Germany.
  • Frahm C; GerontoSys JenAge Consortium, D-07745, Jena, Germany.
  • Priebe S; Genome Analysis Lab, Leibniz Institute on Aging-Fritz-Lipmann-Institute, D-07745, Jena, Germany.
  • Baumgart M; GerontoSys JenAge Consortium, D-07745, Jena, Germany.
  • Hartmann N; Hans Berger Department of Neurology, Jena University Hospital, D-07747, Jena, Germany.
  • Marthandan S; GerontoSys JenAge Consortium, D-07745, Jena, Germany.
  • Menzel U; Systems Biology and Bioinformatics Group, Leibniz Institute for Natural Product Research and Infection Biology-Hans-Knöll-Institute, D-07745, Jena, Germany.
  • Müller J; GerontoSys JenAge Consortium, D-07745, Jena, Germany.
  • Schmidt S; Biology of Ageing Lab, Leibniz Institute on Aging-Fritz-Lipmann-Institute, D-07745, Jena, Germany.
  • Ast V; GerontoSys JenAge Consortium, D-07745, Jena, Germany.
  • Caliebe A; Molecular Genetics Lab, Leibniz Institute on Aging-Fritz-Lipmann-Institute, D-07745, Jena, Germany.
  • König R; GerontoSys JenAge Consortium, D-07745, Jena, Germany.
  • Krawczak M; Imageing Facility, Leibniz Institute on Aging-Fritz-Lipmann-Institute, D-07745, Jena, Germany.
  • Ristow M; GerontoSys JenAge Consortium, D-07745, Jena, Germany.
  • Schuster S; Systems Biology and Bioinformatics Group, Leibniz Institute for Natural Product Research and Infection Biology-Hans-Knöll-Institute, D-07745, Jena, Germany.
  • Cellerino A; Hans Berger Department of Neurology, Jena University Hospital, D-07747, Jena, Germany.
  • Diekmann S; GerontoSys JenAge Consortium, D-07745, Jena, Germany.
  • Englert C; Hans Berger Department of Neurology, Jena University Hospital, D-07747, Jena, Germany.
  • Hemmerich P; Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, D-07747, Jena, Germany.
  • Sühnel J; Network Modeling, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, D-07745, Jena, Germany.
  • Guthke R; Institute for Medical Informatics and Statistics, Christian-Albrechts-University Kiel, D-24105, Kiel, Germany.
  • Witte OW; Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, D-07747, Jena, Germany.
  • Platzer M; Network Modeling, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute, D-07745, Jena, Germany.
  • Ruppin E; Institute for Medical Informatics and Statistics, Christian-Albrechts-University Kiel, D-24105, Kiel, Germany.
  • Kaleta C; GerontoSys JenAge Consortium, D-07745, Jena, Germany.
Nat Commun ; 9(1): 327, 2018 01 30.
Article em En | MEDLINE | ID: mdl-29382830
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Doenças Cardiovasculares / Doenças Neurodegenerativas / Diabetes Mellitus / Transcriptoma / Neoplasias Limite: Aged80 Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Doenças Cardiovasculares / Doenças Neurodegenerativas / Diabetes Mellitus / Transcriptoma / Neoplasias Limite: Aged80 Idioma: En Ano de publicação: 2018 Tipo de documento: Article