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BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor.
Ozer, Hatice Gulcin; El-Gamal, Dalia; Powell, Ben; Hing, Zachary A; Blachly, James S; Harrington, Bonnie; Mitchell, Shaneice; Grieselhuber, Nicole R; Williams, Katie; Lai, Tzung-Huei; Alinari, Lapo; Baiocchi, Robert A; Brinton, Lindsey; Baskin, Elizabeth; Cannon, Matthew; Beaver, Larry; Goettl, Virginia M; Lucas, David M; Woyach, Jennifer A; Sampath, Deepa; Lehman, Amy M; Yu, Lianbo; Zhang, Jiazhong; Ma, Yan; Zhang, Ying; Spevak, Wayne; Shi, Songyuan; Severson, Paul; Shellooe, Rafe; Carias, Heidi; Tsang, Garson; Dong, Ken; Ewing, Todd; Marimuthu, Adhirai; Tantoy, Christina; Walters, Jason; Sanftner, Laura; Rezaei, Hamid; Nespi, Marika; Matusow, Bernice; Habets, Gaston; Ibrahim, Prabha; Zhang, Chao; Mathé, Ewy A; Bollag, Gideon; Byrd, John C; Lapalombella, Rosa.
Afiliação
  • Ozer HG; Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio.
  • El-Gamal D; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Powell B; Plexxikon Inc., Berkeley, California.
  • Hing ZA; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Blachly JS; Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio.
  • Harrington B; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Mitchell S; College of Veterinary Medicine, The Ohio State University, Columbus, Ohio.
  • Grieselhuber NR; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Williams K; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Lai TH; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Alinari L; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Baiocchi RA; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Brinton L; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Baskin E; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Cannon M; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Beaver L; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Goettl VM; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Lucas DM; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Woyach JA; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Sampath D; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Lehman AM; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio.
  • Yu L; Center for Biostatistics, The Ohio State University, Columbus, Ohio.
  • Zhang J; Center for Biostatistics, The Ohio State University, Columbus, Ohio.
  • Ma Y; Plexxikon Inc., Berkeley, California.
  • Zhang Y; Plexxikon Inc., Berkeley, California.
  • Spevak W; Plexxikon Inc., Berkeley, California.
  • Shi S; Plexxikon Inc., Berkeley, California.
  • Severson P; Plexxikon Inc., Berkeley, California.
  • Shellooe R; Plexxikon Inc., Berkeley, California.
  • Carias H; Plexxikon Inc., Berkeley, California.
  • Tsang G; Plexxikon Inc., Berkeley, California.
  • Dong K; Plexxikon Inc., Berkeley, California.
  • Ewing T; Plexxikon Inc., Berkeley, California.
  • Marimuthu A; Plexxikon Inc., Berkeley, California.
  • Tantoy C; Plexxikon Inc., Berkeley, California.
  • Walters J; Plexxikon Inc., Berkeley, California.
  • Sanftner L; Plexxikon Inc., Berkeley, California.
  • Rezaei H; Plexxikon Inc., Berkeley, California.
  • Nespi M; Plexxikon Inc., Berkeley, California.
  • Matusow B; Plexxikon Inc., Berkeley, California.
  • Habets G; Plexxikon Inc., Berkeley, California.
  • Ibrahim P; Plexxikon Inc., Berkeley, California.
  • Zhang C; Plexxikon Inc., Berkeley, California.
  • Mathé EA; Plexxikon Inc., Berkeley, California.
  • Bollag G; Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio.
  • Byrd JC; Plexxikon Inc., Berkeley, California.
  • Lapalombella R; Division of Hematology, Department of Medicine, The Ohio State University, Columbus, Ohio. rosa.lapalombella@osumc.edu john.byrd@osumc.edu.
Cancer Discov ; 8(4): 458-477, 2018 04.
Article em En | MEDLINE | ID: mdl-29386193
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Pirróis / Fatores de Transcrição / Proteínas Nucleares / Leucemia Linfocítica Crônica de Células B / Transdução de Sinais / Regulação Leucêmica da Expressão Gênica / Isoxazóis Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piridinas / Pirróis / Fatores de Transcrição / Proteínas Nucleares / Leucemia Linfocítica Crônica de Células B / Transdução de Sinais / Regulação Leucêmica da Expressão Gênica / Isoxazóis Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article