Family with sequence similarity 13, member A modulates adipocyte insulin signaling and preserves systemic metabolic homeostasis.

Wardhana, Donytra Arby; Ikeda, Koji; Barinda, Agian Jeffilano; Nugroho, Dhite Bayu; Qurania, Kikid Rucira; Yagi, Keiko; Miyata, Keishi; Oike, Yuichi; Hirata, Ken-Ichi; Emoto, Noriaki

Wardhana, Donytra Arby; Ikeda, Koji; Barinda, Agian Jeffilano; Nugroho, Dhite Bayu; Qurania, Kikid Rucira; Yagi, Keiko; Miyata, Keishi; Oike, Yuichi; Hirata, Ken-Ichi; Emoto, Noriaki.

Afiliação

Wardhana DA; Department of Clinical Pharmacy, Kobe Pharmaceutical University, Higashinada, 658-8558 Kobe, Japan.
Ikeda K; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Chuo, 6500017 Kobe, Japan.
Barinda AJ; Department of Clinical Pharmacy, Kobe Pharmaceutical University, Higashinada, 658-8558 Kobe, Japan; ikedak-circ@umin.ac.jp.
Nugroho DB; Department of Clinical Pharmacy, Kobe Pharmaceutical University, Higashinada, 658-8558 Kobe, Japan.
Qurania KR; Department of Clinical Pharmacy, Kobe Pharmaceutical University, Higashinada, 658-8558 Kobe, Japan.
Yagi K; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Chuo, 6500017 Kobe, Japan.
Miyata K; Department of Clinical Pharmacy, Kobe Pharmaceutical University, Higashinada, 658-8558 Kobe, Japan.
Oike Y; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Chuo, 6500017 Kobe, Japan.
Hirata KI; Department of Clinical Pharmacy, Kobe Pharmaceutical University, Higashinada, 658-8558 Kobe, Japan.
Emoto N; Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, Chuo-ku, 860-8556 Kumamoto, Japan.

Proc Natl Acad Sci U S A ; 115(7): 1529-1534, 2018 02 13.

Article em En | MEDLINE | ID: mdl-29386390

Assuntos

Adipócitos/metabolismo; Proteínas Ativadoras de GTPase/fisiologia; Resistência à Insulina; Insulina/metabolismo; Doenças Metabólicas/etiologia; Obesidade/complicações; Adipócitos/citologia; Animais; Feminino; Glucose/metabolismo; Células HEK293; Homeostase; Humanos; Proteínas Substratos do Receptor de Insulina/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Transdução de Sinais

Palavras-chave

IRS1; adipocyte; insulin signaling; metabolic disorder; obesity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Adipócitos / Proteínas Ativadoras de GTPase / Insulina / Doenças Metabólicas / Obesidade Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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