NF­&#954;B is a key modulator in the signaling pathway of Borrelia burgdorferi BmpA­induced inflammatory chemokines in murine microglia BV2 cells.

Zhao, Zhenyu; Tao, Lvyan; Liu, Aihua; Ma, Mingbiao; Li, Haiyi; Zhao, Hua; Yang, Jiaru; Wang, Shiming; Jin, Yirong; Shao, Xian; Bao, Fukai

NFκB is a key modulator in the signaling pathway of Borrelia burgdorferi BmpAinduced inflammatory chemokines in murine microglia BV2 cells.

Zhao, Zhenyu; Tao, Lvyan; Liu, Aihua; Ma, Mingbiao; Li, Haiyi; Zhao, Hua; Yang, Jiaru; Wang, Shiming; Jin, Yirong; Shao, Xian; Bao, Fukai.

Afiliação

Zhao Z; School of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Tao L; School of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Liu A; School of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Ma M; School of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Li H; Faculty of Public Health, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Zhao H; School of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Yang J; School of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Wang S; School of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Jin Y; School of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Shao X; School of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.
Bao F; School of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan 650500, P.R. China.

Mol Med Rep ; 17(4): 4953-4958, 2018 04.

Article em En | MEDLINE | ID: mdl-29393443

Assuntos

Proteínas de Bactérias/metabolismo; Quimiocinas/metabolismo; Mediadores da Inflamação/metabolismo; Microglia/metabolismo; NF-kappa B/metabolismo; Transdução de Sinais; Animais; Proteínas de Bactérias/farmacologia; Borrelia burgdorferi/metabolismo; Linhagem Celular; Expressão Gênica; Doença de Lyme/genética; Doença de Lyme/metabolismo; Doença de Lyme/microbiologia; Camundongos; Microglia/efeitos dos fármacos; NF-kappa B/genética; Proteínas Recombinantes

Palavras-chave

Lyme neuroborreliosis; Borrelia burgdorferi; nuclear factor κ-B; recombinant basic membrane protein A; BV2 microglia; pathogenesis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Transdução de Sinais / NF-kappa B / Microglia / Mediadores da Inflamação / Quimiocinas Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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