Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

Vernon, Robert McCoy; Chong, Paul Andrew; Tsang, Brian; Kim, Tae Hun; Bah, Alaji; Farber, Patrick; Lin, Hong; Forman-Kay, Julie Deborah

Vernon, Robert McCoy; Chong, Paul Andrew; Tsang, Brian; Kim, Tae Hun; Bah, Alaji; Farber, Patrick; Lin, Hong; Forman-Kay, Julie Deborah.

Afiliação

Vernon RM; Program in Molecular Medicine, Hospital for Sick Children, Toronto, Canada.
Chong PA; Program in Molecular Medicine, Hospital for Sick Children, Toronto, Canada.
Tsang B; Program in Molecular Medicine, Hospital for Sick Children, Toronto, Canada.
Kim TH; Department of Biochemistry, University of Toronto, Toronto, Canada.
Bah A; Program in Molecular Medicine, Hospital for Sick Children, Toronto, Canada.
Farber P; Program in Molecular Medicine, Hospital for Sick Children, Toronto, Canada.
Lin H; Program in Molecular Medicine, Hospital for Sick Children, Toronto, Canada.
Forman-Kay JD; Program in Molecular Medicine, Hospital for Sick Children, Toronto, Canada.

Elife ; 72018 02 09.

Article em En | MEDLINE | ID: mdl-29424691

Assuntos

Proteínas Intrinsicamente Desordenadas/química; Proteínas Intrinsicamente Desordenadas/metabolismo; Organelas/química; Organelas/metabolismo; Dobramento de Proteína; Interações Hidrofóbicas e Hidrofílicas; Ligação Proteica; Eletricidade Estática

Palavras-chave

bioinformatics; computational biology; human; molecular biophysics; pi interactions; prediction; protein interactions; protein phase separation; protein structure; structural biology; systems biology

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Organelas / Dobramento de Proteína / Proteínas Intrinsicamente Desordenadas Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google