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The presence of the 1068 G>A variant of P2X7 receptors is associated to an increase in IL-1Ra levels, insulin secretion and pancreatic ß-cell function but not with glycemic control in type 2 diabetes patients.
Uresti-Rivera, Edith Elena; García-Jacobo, Rocío Edith; Méndez-Cabañas, José Alfredo; Gaytan-Medina, Laura Elizabeth; Cortez-Espinosa, Nancy; Portales-Pérez, Diana Patricia; González-Amaro, Roberto; Enciso-Moreno, José Antonio; García-Hernández, Mariana Haydee.
Afiliação
  • Uresti-Rivera EE; Laboratory of Immunology and Cellular and Molecular Biology, Faculty of Chemical Sciences, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.
  • García-Jacobo RE; Unidad de Investigacion Biomedica, Delegación Zacatecas, Instituto Mexicano del Seguro Social, IMSS, Mexico.
  • Méndez-Cabañas JA; Molecular Biophysics Laboratory, Physics Institute, Universidad Autónoma de San Luis Potosí, , San Luis Potosí, SLP, Mexico.
  • Gaytan-Medina LE; Unidad de Investigacion Biomedica, Delegación Zacatecas, Instituto Mexicano del Seguro Social, IMSS, Mexico.
  • Cortez-Espinosa N; Laboratory of Immunology and Cellular and Molecular Biology, Faculty of Chemical Sciences, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.
  • Portales-Pérez DP; Laboratory of Immunology and Cellular and Molecular Biology, Faculty of Chemical Sciences, Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.
  • González-Amaro R; Research Center for Health Sciences and Biomedicine, UASLP, San Luis Potosi, Mexico.
  • Enciso-Moreno JA; Unidad de Investigacion Biomedica, Delegación Zacatecas, Instituto Mexicano del Seguro Social, IMSS, Mexico.
  • García-Hernández MH; Unidad de Investigacion Biomedica, Delegación Zacatecas, Instituto Mexicano del Seguro Social, IMSS, Mexico. Electronic address: mariana.garciah@imss.gob.mx.
Gene ; 652: 1-6, 2018 Apr 30.
Article em En | MEDLINE | ID: mdl-29425823
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo de Nucleotídeo Único / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Proteína Antagonista do Receptor de Interleucina 1 / Receptores Purinérgicos P2X7 Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo de Nucleotídeo Único / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Proteína Antagonista do Receptor de Interleucina 1 / Receptores Purinérgicos P2X7 Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article