Natural and Vaccine-Induced Acquisition of Cross-Reactive IgG-Inhibiting ICAM-1-Specific Binding of a Plasmodium falciparum PfEMP1 Subtype Associated Specifically with Cerebral Malaria.

Olsen, Rebecca W; Ecklu-Mensah, Gertrude; Bengtsson, Anja; Ofori, Michael F; Lusingu, John P A; Castberg, Filip C; Hviid, Lars; Adams, Yvonne; Jensen, Anja T R

Olsen, Rebecca W; Ecklu-Mensah, Gertrude; Bengtsson, Anja; Ofori, Michael F; Lusingu, John P A; Castberg, Filip C; Hviid, Lars; Adams, Yvonne; Jensen, Anja T R.

Afiliação

Olsen RW; Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Ecklu-Mensah G; Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Bengtsson A; Department of Immunology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana.
Ofori MF; Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Lusingu JPA; Department of Immunology, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana.
Castberg FC; National Institute for Medical Research, Tanga Centre, Tanga City, Tanzania.
Hviid L; Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Adams Y; Department of Clinical Microbiology, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
Jensen ATR; Centre for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Infect Immun ; 86(4)2018 04.

Article em En | MEDLINE | ID: mdl-29426042

Assuntos

Imunoglobulina G/imunologia; Molécula 1 de Adesão Intercelular/metabolismo; Malária Cerebral/imunologia; Malária Falciparum/imunologia; Plasmodium falciparum/imunologia; Proteínas de Protozoários/imunologia; Proteínas de Protozoários/metabolismo; Adolescente; Motivos de Aminoácidos; Anticorpos Neutralizantes/imunologia; Anticorpos Antiprotozoários/imunologia; Antígenos de Protozoários/imunologia; Sítios de Ligação; Criança; Pré-Escolar; Reações Cruzadas/imunologia; Gana; Humanos; Imunoglobulina G/metabolismo; Lactente; Vacinas Antimaláricas/imunologia; Malária Cerebral/metabolismo; Malária Cerebral/parasitologia; Malária Falciparum/metabolismo; Malária Falciparum/parasitologia; Ligação Proteica/imunologia; Domínios e Motivos de Interação entre Proteínas; Proteínas de Protozoários/química; Tanzânia

Palavras-chave

DBLß cross-reactive antibodies; ICAM-1-binding motif; PfEMP1; Plasmodium falciparum; adhesion inhibition

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Imunoglobulina G / Proteínas de Protozoários / Malária Falciparum / Malária Cerebral / Molécula 1 de Adesão Intercelular Tipo de estudo: Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Humans / Infant País/Região como assunto: Africa Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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