Mechanisms of altered renal sodium handling in age-related hypertension.
Am J Physiol Renal Physiol
; 315(1): F1-F6, 2018 07 01.
Article
em En
| MEDLINE
| ID: mdl-29442548
ABSTRACT
The prevalence of hypertension rises with age to approximately two out of three adults over the age of 60 in the United States. Although the mechanisms underlying age-related hypertension are incompletely understood, sodium homeostasis is critical to the long-term regulation of blood pressure and there is strong evidence that aging is associated with alterations in renal sodium handling. This minireview focuses on recent advancements in our understanding of the vascular, neurohumoral, and renal mechanisms that influence sodium homeostasis and promote age-related hypertension.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sódio
/
Pressão Sanguínea
/
Envelhecimento
/
Hipertensão
/
Rim
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Animals
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article