Pold3 is required for genomic stability and telomere integrity in embryonic stem cells and meiosis.

Zhou, Zhongcheng; Wang, Lingling; Ge, Feixiang; Gong, Peng; Wang, Hua; Wang, Feng; Chen, Lingyi; Liu, Lin

Zhou, Zhongcheng; Wang, Lingling; Ge, Feixiang; Gong, Peng; Wang, Hua; Wang, Feng; Chen, Lingyi; Liu, Lin.

Afiliação

Zhou Z; State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Wang L; Department of Cell Biology and Genetics, The Key Laboratory of Bioactive Materials Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China.
Ge F; Department of Cell Biology and Genetics, The Key Laboratory of Bioactive Materials Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China.
Gong P; State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Wang H; Department of Cell Biology and Genetics, The Key Laboratory of Bioactive Materials Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China.
Wang F; State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Chen L; Department of Cell Biology and Genetics, The Key Laboratory of Bioactive Materials Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China.
Liu L; State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.

Nucleic Acids Res ; 46(7): 3468-3486, 2018 04 20.

Article em En | MEDLINE | ID: mdl-29447390

Assuntos

DNA Polimerase III/genética; Replicação do DNA/genética; Células-Tronco Embrionárias/metabolismo; Instabilidade Genômica/genética; Telômero/genética; Animais; Proteínas Mutadas de Ataxia Telangiectasia/genética; Sistemas CRISPR-Cas/genética; Quebras de DNA de Cadeia Dupla; Dano ao DNA/genética; Reparo do DNA/genética; Meiose/genética; Camundongos Knockout; Proteínas de Ligação a Telômeros/genética; Proteína 1 de Ligação à Proteína Supressora de Tumor p53/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Telômero / Instabilidade Genômica / DNA Polimerase III / Replicação do DNA / Células-Tronco Embrionárias Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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