NIT1 suppresses tumour proliferation by activating the TGFß1-Smad2/3 signalling pathway in colorectal cancer.

Lin, Chun; Zhang, Jianming; Lu, Yanxia; Li, Xiaomin; Zhang, Wenjuan; Zhang, Wei; Lin, Weihao; Zheng, Lin; Li, Xuenong

Lin, Chun; Zhang, Jianming; Lu, Yanxia; Li, Xiaomin; Zhang, Wenjuan; Zhang, Wei; Lin, Weihao; Zheng, Lin; Li, Xuenong.

Afiliação

Lin C; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zhang J; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Lu Y; Department of Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Li X; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zhang W; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zhang W; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Lin W; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Zheng L; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Li X; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.

Cell Death Dis ; 9(3): 263, 2018 02 15.

Article em En | MEDLINE | ID: mdl-29449642

Assuntos

Aminoidrolases/metabolismo; Proliferação de Células; Neoplasias Colorretais/enzimologia; Proteína Smad2/metabolismo; Proteína Smad3/metabolismo; Fator de Crescimento Transformador beta1/metabolismo; Aminoidrolases/genética; Animais; Apoptose; Sítios de Ligação; Células CACO-2; Pontos de Checagem do Ciclo Celular; Neoplasias Colorretais/genética; Neoplasias Colorretais/patologia; Feminino; Regulação Enzimológica da Expressão Gênica; Regulação Neoplásica da Expressão Gênica; Células HCT116; Células HEK293; Células HT29; Humanos; Masculino; Camundongos Endogâmicos BALB C; Camundongos Nus; Pessoa de Meia-Idade; Regiões Promotoras Genéticas; Transdução de Sinais; Carga Tumoral

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proliferação de Células / Proteína Smad2 / Proteína Smad3 / Fator de Crescimento Transformador beta1 / Aminoidrolases Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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