What is the optimal initial management of the older MCL patient?
Best Pract Res Clin Haematol
; 31(1): 99-104, 2018 03.
Article
em En
| MEDLINE
| ID: mdl-29452672
ABSTRACT
The current first line treatment of a patient with mantle cell lymphoma (MCL) is often considered as too toxic for elderly patients. The elderly, however, comprise the majority of the patients with MCL. The results of several recent studies have shown that the outcome of this patient group is not as dismal as in the past. Indeed, if patients are not considered frail, and can tolerate rituximab and moderate intensive chemotherapy such as R-CHOP followed by rituximab maintenance or R-bendamustine, a 4-year overall survival of >80% can be achieved. In this chapter the developments of the regimens, resulting in the standard treatment options for these patients, are discussed.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Protocolos de Quimioterapia Combinada Antineoplásica
/
Linfoma de Célula do Manto
Limite:
Aged
/
Humans
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article