ST2 as a predictor of late ventricular remodeling after myocardial infarction.
Int J Cardiol
; 259: 40-42, 2018 05 15.
Article
em En
| MEDLINE
| ID: mdl-29486997
ABSTRACT
Out of 163 STEMI patients, 33 presented left ventricular remodeling (LVR) as assessed by multiple cardiac magnetic resonance (CMR) scans. LVR patients were identified as EarlyLVR (LVR occurring between baseline and 3â¯months) or LateLVR (LVR occurring between 3â¯months and one year), and matched to non-remodeler patients in term of age, gender, anterior infarction, baseline LV ejection fraction and infarct size. ST2 and NT-proBNP were measured at baseline and 3â¯months. Systolic wall stress (SWS) was calculated by CMR. At baseline, mean levels of ST2, NT-proBNP and SWS were 67.1⯱â¯54.1â¯ng/mL, 1529⯱â¯1702â¯ng/L and 17.9⯱â¯7.1 103â¯N·m-2, respectively, and did not differ among the groups. At 3â¯months, EarlyLVR patients presented significant higher ST2, NT-proBNP and SWS (31.6⯱â¯12.7â¯ng/mL, 1142⯱â¯1069â¯ng/L, 25.5⯱â¯9.7 103â¯N·m-2), compared to the corresponding non-remodelers (20.5⯱â¯8.6â¯ng/mL, 397⯱â¯273â¯ng/L, 18⯱â¯7.3 103â¯N·m-2; with pâ¯=â¯0.017, 0.040, and 0.036, respectively). LateLVR patients presented higher ST2 at 3â¯months than their non-remodelers (33.6⯱â¯15.9 versus 23.66⯱â¯8.7â¯ng/mL, pâ¯=â¯0.046), while NT-proBNP and SWS were not different between groups at both timepoints.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Remodelação Ventricular
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Infarto do Miocárdio com Supradesnível do Segmento ST
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Proteína 1 Semelhante a Receptor de Interleucina-1
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article