Real time indocyanin green near infrared lymphangiography for the reduction of drainage volume after neck dissection.
Oral Oncol
; 78: 52-55, 2018 03.
Article
em En
| MEDLINE
| ID: mdl-29496058
ABSTRACT
BACKGROUND:
To investigate the role of indocyanine green (ICG) lymphangiography in the reduction of drainage after neck dissection.METHODS:
Patients with oral cavity squamous cell carcinoma were randomized into Group A (study group) and Group B (control). In the study group, upon the completion of neck dissection, a total of 2.5â¯mg of ICG was injected submucosally at the four quadrants around the tumour. Another 2.5â¯mg of ICG was injected subdermally in the groin bilaterally. The neck was screened using Near Infrared fluorescence. The presence of lymphatic leakage was noted and plicated with silk stitches. The total drainage volume of post-operative day 1, day 2 and the total accumulated volume until drain removal was measured.RESULTS:
Twenty-two patients (Group A, nâ¯=â¯12; Group B, nâ¯=â¯10) were recruited. All patients in Group A had at least one site of lymphatic leakage identified. One patient in Group B developed chylous fistula and was excluded from analysis. The mean total drain output for day 1 and 2 after surgery, as well as the mean total output before drain removal, were significantly lower in Group A (22.4â¯ml vs. 86.2â¯ml [pâ¯=â¯.02]; 14.2â¯ml vs. 72.8â¯ml [pâ¯=â¯.02]; and 58.4â¯ml vs. 392â¯ml [pâ¯=â¯.01], respectively), allowing earlier drain removal (2.2â¯days vs. 7.2â¯days, pâ¯=â¯.02).CONCLUSIONS:
Intra-operative ICG lymphangiography is useful in the reduction of drainage volume after neck dissection for caners in the head and neck region.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esvaziamento Cervical
/
Linfografia
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Drenagem
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Verde de Indocianina
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Linfonodos
Tipo de estudo:
Clinical_trials
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article