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Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search.
Ding, Hong; Lu, Wen Chao; Hu, Jun Chi; Liu, Yu-Chih; Zhang, Chen Hua; Lian, Fu Lin; Zhang, Nai Xia; Meng, Fan Wang; Luo, Cheng; Chen, Kai Xian.
Afiliação
  • Ding H; School of Pharmacy, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, China. hding@simm.ac.cn.
  • Lu WC; CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. hding@simm.ac.cn.
  • Hu JC; CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. wenchaolu@simm.ac.cn.
  • Liu YC; CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. hujunchi@simm.ac.cn.
  • Zhang CH; Shanghai ChemPartner Co., Ltd., #5 Building, 998 Halei Road, Shanghai 201203, China. yzhliu@chempartner.com.
  • Lian FL; Shanghai ChemPartner Co., Ltd., #5 Building, 998 Halei Road, Shanghai 201203, China. chhzhang@chempartner.com.
  • Zhang NX; CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. fulinlian1986@simm.ac.cn.
  • Meng FW; CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. nxzhang@simm.ac.cn.
  • Luo C; CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China. mengf9@mcmaster.ca.
  • Chen KX; Department of Chemistry and Chemical Biology, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4L8, Canada. mengf9@mcmaster.ca.
Molecules ; 23(3)2018 Mar 02.
Article em En | MEDLINE | ID: mdl-29498708
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiofenos / Histona-Lisina N-Metiltransferase / Inibidores Enzimáticos / Impressão Molecular / Anilidas / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiofenos / Histona-Lisina N-Metiltransferase / Inibidores Enzimáticos / Impressão Molecular / Anilidas / Antineoplásicos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article