Multimodal lipid-lowering treatment in pediatric patients with homozygous familial hypercholesterolemia-target attainment requires further increase of intensity.

Klaus, Günter; Taylan, Christina; Büscher, Rainer; Schmitt, Claus Peter; Pape, Lars; Oh, Jun; Driemeyer, Joenna; Galiano, Matthias; König, Jens; Schürfeld, Carsten; Spitthöver, Ralf; Schaefer, Juergen R; Weber, Lutz T; Heibges, Andreas; Klingel, Reinhard

Klaus, Günter; Taylan, Christina; Büscher, Rainer; Schmitt, Claus Peter; Pape, Lars; Oh, Jun; Driemeyer, Joenna; Galiano, Matthias; König, Jens; Schürfeld, Carsten; Spitthöver, Ralf; Schaefer, Juergen R; Weber, Lutz T; Heibges, Andreas; Klingel, Reinhard.

Afiliação

Klaus G; Renal Unit, KfH Pediatric Kidney Centre, and Centre for Undiagnosed and Rare Diseases, Marburg, Germany.
Taylan C; Pediatric Nephrology, Children's and Adolescents' Hospital, University Hospital of Cologne, Cologne, Germany.
Büscher R; Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Essen University Hospital, Essen, Germany.
Schmitt CP; Pediatric Nephrology, University Hospital for Pediatric and Adolescent Medicine, Heidelberg, Germany.
Pape L; Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine and Dermatology, Hannover Medical School, Hannover, Germany.
Oh J; Center for Obstetrics and Pediatrics, Department of Pediatrics, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Driemeyer J; Center for Obstetrics and Pediatrics, Department of Pediatrics, University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Galiano M; Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Erlangen University Hospital, Erlangen, Germany.
König J; Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Münster University Hospital, Münster, Germany.
Schürfeld C; Center for Nephrology and Dialysis, Saarlouis, Germany.
Spitthöver R; Dialysis and Lipid Center North Rhine, Essen, Germany.
Schaefer JR; Renal Unit, KfH Pediatric Kidney Centre, and Centre for Undiagnosed and Rare Diseases, Marburg, Germany.
Weber LT; Pediatric Nephrology, Children's and Adolescents' Hospital, University Hospital of Cologne, Cologne, Germany.
Heibges A; Apheresis Research Institute, Stadtwaldguertel 77, 50935, Cologne, Germany.
Klingel R; Apheresis Research Institute, Stadtwaldguertel 77, 50935, Cologne, Germany. klingel@apheresis-research.org.

Pediatr Nephrol ; 33(7): 1199-1208, 2018 07.

Article em En | MEDLINE | ID: mdl-29502162

Assuntos

Anticolesterolemiantes/uso terapêutico; Remoção de Componentes Sanguíneos/métodos; Doenças Cardiovasculares/prevenção & controle; LDL-Colesterol/sangue; Hiperlipoproteinemia Tipo II/terapia; Adolescente; Doenças Cardiovasculares/sangue; Doenças Cardiovasculares/etiologia; Criança; Pré-Escolar; Terapia Combinada/métodos; Aconselhamento/métodos; Feminino; Alemanha; Estilo de Vida Saudável; Heterozigoto; Humanos; Hiperlipoproteinemia Tipo II/sangue; Hiperlipoproteinemia Tipo II/complicações; Hiperlipoproteinemia Tipo II/genética; Masculino; Receptores de LDL/genética; Estudos Retrospectivos; Fatores de Risco; Resultado do Tratamento; Adulto Jovem

Palavras-chave

Children; Familial hypercholesterolemia; LDL-cholesterol; Lipoprotein apheresis prevention; Treatment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Remoção de Componentes Sanguíneos / Doenças Cardiovasculares / Hiperlipoproteinemia Tipo II / LDL-Colesterol / Anticolesterolemiantes Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male País/Região como assunto: Europa Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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