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Activation of AMPK by simvastatin inhibited breast tumor angiogenesis via impeding HIF-1α-induced pro-angiogenic factor.
Wang, Ji-Chang; Li, Xiong-Xiong; Sun, Xin; Li, Guang-Yue; Sun, Jing-Lan; Ye, Yuan-Peng; Cong, Long-Long; Li, Wei-Ming; Lu, Shao-Ying; Feng, Jun; Liu, Pei-Jun.
Afiliação
  • Wang JC; Department of Vascular Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
  • Li XX; Center for Translational Medicine, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
  • Sun X; Department of Breast Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
  • Li GY; Department of Thoracic Surgery and Oncology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
  • Sun JL; Department of Science and Technology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
  • Ye YP; Department of Vascular Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
  • Cong LL; Department of Vascular Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
  • Li WM; Department of Vascular Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
  • Lu SY; Department of Vascular Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
  • Feng J; Department of Vascular Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
  • Liu PJ; Department of Vascular Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Cancer Sci ; 109(5): 1627-1637, 2018 May.
Article em En | MEDLINE | ID: mdl-29532562
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinvastatina / Subunidade alfa do Fator 1 Induzível por Hipóxia / Proteínas Quinases Ativadas por AMP / Neovascularização Patológica Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinvastatina / Subunidade alfa do Fator 1 Induzível por Hipóxia / Proteínas Quinases Ativadas por AMP / Neovascularização Patológica Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article