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Synthesis, molecular docking study and in vitro thymidine phosphorylase inhibitory potential of oxadiazole derivatives.
Ullah, Hayat; Rahim, Fazal; Taha, Muhammad; Uddin, Imad; Wadood, Abdul; Shah, Syed Adnan Ali; Farooq, Rai Khalid; Nawaz, Mohsan; Wahab, Zainul; Khan, Khalid Mohammed.
Afiliação
  • Ullah H; Department of Chemistry, Hazara University, Mansehra 21300, Pakistan.
  • Rahim F; Department of Chemistry, Hazara University, Mansehra 21300, Pakistan. Electronic address: fazalstar@gmail.com.
  • Taha M; Department of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 31441, Dammam, Saudi Arabia. Electronic address: mtaha@iau.edu.sa.
  • Uddin I; Department of Chemistry, Hazara University, Mansehra 21300, Pakistan.
  • Wadood A; Department of Biochemistry, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan.
  • Shah SAA; Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA (UiTM), Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor, Malaysia; Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor D.E., Malaysia.
  • Farooq RK; Department of Neuroscience Research, Institute of Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.
  • Nawaz M; Department of Chemistry, Hazara University, Mansehra 21300, Pakistan.
  • Wahab Z; Department of Conservation Sciences, Hazara University, Mansehra 21300, Pakistan.
  • Khan KM; Department of Clinical Pharmacy, Institute for Research and Medical Consultations (IRMC), Imam Abdulrahman Bin Faisal University, P.O. Box 31441, Dammam, Saudi Arabia; H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi
Bioorg Chem ; 78: 58-67, 2018 08.
Article em En | MEDLINE | ID: mdl-29533215
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxidiazóis / Timidina Fosforilase / Inibidores Enzimáticos / Simulação de Acoplamento Molecular Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxidiazóis / Timidina Fosforilase / Inibidores Enzimáticos / Simulação de Acoplamento Molecular Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article