CD4+ &#945;ß T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuries.

Du, Bin; Ding, You-Quan; Xiao, Xia; Ren, Hong-Yi; Su, Bing-Yin; Qi, Jian-Guo

CD4+ αß T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuries.

Du, Bin; Ding, You-Quan; Xiao, Xia; Ren, Hong-Yi; Su, Bing-Yin; Qi, Jian-Guo.

Afiliação

Du B; Department of Histology, Embryology and Neurobiology, West China School of Preclinical and Forensic Medicine, Sichuan University, No 17, Section 3, South Ren-min road, Chengdu, Sichuan, 610041, China.
Ding YQ; Department of Histology, Embryology and Neurobiology, West China School of Preclinical and Forensic Medicine, Sichuan University, No 17, Section 3, South Ren-min road, Chengdu, Sichuan, 610041, China.
Xiao X; Department of Histology, Embryology and Neurobiology, West China School of Preclinical and Forensic Medicine, Sichuan University, No 17, Section 3, South Ren-min road, Chengdu, Sichuan, 610041, China.
Ren HY; Department of Histology, Embryology and Neurobiology, West China School of Preclinical and Forensic Medicine, Sichuan University, No 17, Section 3, South Ren-min road, Chengdu, Sichuan, 610041, China.
Su BY; Sichuan Province Development and Regeneration Key Laboratory, Chengdu Medical College, Chengdu, Sichuan, 610500, China.
Qi JG; Department of Histology, Embryology and Neurobiology, West China School of Preclinical and Forensic Medicine, Sichuan University, No 17, Section 3, South Ren-min road, Chengdu, Sichuan, 610041, China. jgqi@scu.edu.cn.

J Neuroinflammation ; 15(1): 81, 2018 Mar 15.

Article em En | MEDLINE | ID: mdl-29544518

Assuntos

Linfócitos T CD4-Positivos/fisiologia; Hiperalgesia/etiologia; Hiperalgesia/patologia; Meninges/fisiopatologia; Raízes Nervosas Espinhais/patologia; Neuropatia Tibial/complicações; Animais; Movimento Celular; Modelos Animais de Doenças; Região Lombossacral; Masculino; Infiltração de Neutrófilos/fisiologia; Medição da Dor; Limiar da Dor/fisiologia; Fosfopiruvato Hidratase/metabolismo; Proteína Quinase C/metabolismo; Ratos; Ratos Sprague-Dawley; Receptores de Antígenos de Linfócitos T alfa-beta/metabolismo; Fatores de Tempo

Palavras-chave

CD4+ αß T cell; Chronic pain; Dorsal root; Glia; Leptomeninges; Lymph node; Mechanical allodynia; Neuropathic pain; PKCÎ³+ excitatory interneuron; Peripheral nerve injury

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Raízes Nervosas Espinhais / Linfócitos T CD4-Positivos / Neuropatia Tibial / Hiperalgesia / Meninges Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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