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Ligand channel in pharmacologically stabilized rhodopsin.
Mattle, Daniel; Kuhn, Bernd; Aebi, Johannes; Bedoucha, Marc; Kekilli, Demet; Grozinger, Nathalie; Alker, Andre; Rudolph, Markus G; Schmid, Georg; Schertler, Gebhard F X; Hennig, Michael; Standfuss, Jörg; Dawson, Roger J P.
Afiliação
  • Mattle D; Roche Pharma Research and Early Development, Therapeutic Modalities, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Kuhn B; Laboratory of Biomolecular Research, Department of Biology and Chemistry, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
  • Aebi J; Roche Pharma Research and Early Development, Therapeutic Modalities, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Bedoucha M; Roche Pharma Research and Early Development, Therapeutic Modalities, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Kekilli D; Roche Pharma Research and Early Development, Therapeutic Modalities, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Grozinger N; Laboratory of Biomolecular Research, Department of Biology and Chemistry, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
  • Alker A; Roche Pharma Research and Early Development, Therapeutic Modalities, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Rudolph MG; Roche Pharma Research and Early Development, Therapeutic Modalities, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Schmid G; Roche Pharma Research and Early Development, Therapeutic Modalities, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Schertler GFX; Roche Pharma Research and Early Development, Therapeutic Modalities, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
  • Hennig M; Laboratory of Biomolecular Research, Department of Biology and Chemistry, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland.
  • Standfuss J; Department of Biology, ETH Zurich, 8093 Zurich, Switzerland.
  • Dawson RJP; Roche Pharma Research and Early Development, Therapeutic Modalities, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, 4070 Basel, Switzerland.
Proc Natl Acad Sci U S A ; 115(14): 3640-3645, 2018 04 03.
Article em En | MEDLINE | ID: mdl-29555765
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Conformação Proteica / Rodopsina / Preparações Farmacêuticas / Desenho de Fármacos / Receptores Acoplados a Proteínas G / Estabilidade Proteica Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Conformação Proteica / Rodopsina / Preparações Farmacêuticas / Desenho de Fármacos / Receptores Acoplados a Proteínas G / Estabilidade Proteica Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article